papyriogenin A
isolated from Tetrapanax papyiferum; structure in first source
Networked: 2
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Bio-Agent Context: Research Results
Related Diseases
| 1. | Granuloma
05/01/1983
- " The effects of papyriogenin A or C, 30 mg/kg p.o., on the cotton pellet granuloma test in adrenalectomized rats were similar to those of normal rats. " 05/01/1983
- " The mechanism of anti-inflammatory action of papyriogenin A and C, obtained from Tetrapanax papyriferum, were investigated by the following methods; the cotton pellet granuloma test in normal and adrenalectomized rats, the blockade by anti-glucocorticoids of vascular permeability caused by serotonin in mice and the competition on 5 beta-reduction of steroidal compounds. " 06/01/1982
- " The anti-inflammatory activities of oleanane triterpenoid glycosides, papyrioside L-IIa, L-IIb, L-IIc and L-IId, extracted from Tetrapanax papyriferum (Araliaceae), and their aglycones, papyriogenin A and C and propapyriogenin A1 and A2, were investigated by using the carrageenin-induced edema and the cotton pellet granuloma tests in mice. "
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| 2. | Edema (Dropsy)
05/01/1983
- " The anti-inflammatory activity was observed in the decreasing order; papyriogenin C greater than papyriogenin A on the carrageenin-induced paw edema in mice, as reported in our previous paper. " 06/01/1982
- " The anti-inflammatory activities of oleanane triterpenoid glycosides, papyrioside L-IIa, L-IIb, L-IIc and L-IId, extracted from Tetrapanax papyriferum (Araliaceae), and their aglycones, papyriogenin A and C and propapyriogenin A1 and A2, were investigated by using the carrageenin-induced edema and the cotton pellet granuloma tests in mice. " 05/01/1983
- " In a serotonin-induced paw edema, pretreatment with progesterone (50, 100 and 200 mg/kg) blocked completely the anti-inflammatory effects of papyriogenin A or C at 10 and 50 mg/kg. When actinomycin D (1 and 2 mg/kg) or cycloheximide (6 mg/kg) was given twice, simultaneously with papyriogenin A or C, during the latent period for the manifestation of the anti-inflammatory effect, the anti-inflammatory effects of papyriogenin A and C were blocked completely by s.c. "
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