guanidine carboxamide

RN given refers to parent cpd

Also Known As:

amidinourea; guanidine carboxamide phosphate; guanidine carboxamide, monohydrobromide; guanidine carboxamide, monohydrochloride; guanidine carboxamide, monohydroiodide; guanidine carboxamide, sulfate (1:1); guanidine carboxamide, sulfate (2:1); guanylurea

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - guanidine carboxamide: 5
- Amidines: 14
  - Guanidines: 29
    - Guanidine: 777
      - guanidine carboxamide: 5

Experts

1.	Aukema, Kelly G: 1 article (11/2021)
2.	Martinez-Vaz, Betsy: 1 article (11/2021)
3.	Robinson, Ashley: 1 article (11/2021)
4.	Tassoulas, Lambros J: 1 article (11/2021)
5.	Wackett, Lawrence P: 1 article (11/2021)
6.	Bridges, Kristin N: 1 article (01/2019)
7.	Guchardi, John: 1 article (01/2019)
8.	Holdway, Douglas: 1 article (01/2019)
9.	Kirkwood, Andrea E: 1 article (01/2019)
10.	Pandelides, Zacharias: 1 article (01/2019)

Related Diseases

1.	Type 2 Diabetes Mellitus (MODY) 01/01/2023 - "Environmental Concentrations of the Type 2 Diabetes Medication Metformin and Its Transformation Product Guanylurea in Surface Water and Sediment in Ontario and Quebec, Canada." 11/01/2021 - "Pairwise sequence comparisons and the use of sequence similarity networks allowed fine structure discrimination between the three homologous enzymes and provided insights into the evolutionary origins of guanylurea hydrolase.IMPORTANCE Metformin is a pharmaceutical most prescribed for type 2 diabetes and is now being examined for potential benefits to COVID-19 patients. "
2.	Hyperlipidemias (Hyperlipidemia) 05/01/2017 - "Pharmacokinetics of metformin in the rat: assessment of the effect of hyperlipidemia and evidence for its metabolism to guanylurea."
3.	Breast Neoplasms (Breast Cancer) 01/01/2017 - "A series of novel amidinourea derivatives was synthesized, and the compounds were evaluated as inhibitors of MDA-MB-231 human breast cancer cell proliferation. " 01/01/2017 - "Synthesis and Biological Evaluation of Amidinourea and Triazine Congeners as Inhibitors of MDA-MB-231 Human Breast Cancer Cell Proliferation."
4.	Body Weight Changes 01/01/2019 - "A possible sex-dependent association with body weight changes was also observed in adults following a 165-d full-life cycle exposure to guanylurea alone or in a mixture with metformin. "
5.	COVID-19 11/01/2021 - "Pairwise sequence comparisons and the use of sequence similarity networks allowed fine structure discrimination between the three homologous enzymes and provided insights into the evolutionary origins of guanylurea hydrolase.IMPORTANCE Metformin is a pharmaceutical most prescribed for type 2 diabetes and is now being examined for potential benefits to COVID-19 patients. "

Related Drugs and Biologics

1.	Metformin (Glucophage)
2.	Triazines
3.	Hydrolases
4.	Enzymes