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surfomer
hypolipidemic; RN & structure available in JAMA 1980;243(16):1663
Also Known As:
AOMA; poly(1,2-dicarboxy-3-hexadecyl-1,4-butanediyl); poly(1,2-dicarboxy-3-hexadecyltetramethylene)
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Macromolecular Substances: 97
Polymers: 13051
surfomer: 2
Biomedical and Dental Materials
Polymers: 13051
surfomer: 2
Technology, Industry, and Agriculture
Manufactured Materials
Biomedical and Dental Materials
Polymers: 13051
surfomer: 2
Organic Chemicals: 133
Carboxylic Acids: 973
Acyclic Acids
Dicarboxylic Acids: 108
Succinates: 13
surfomer: 2
Related Diseases
1.
Hypothyroidism
04/01/1987 - "
Maneuvers that augmented intestinal cholesterol uptake (particularly hypothyroidism) appeared to suppress intestinal apoB-48 synthesis by over 40%, while Surfomer (AOMA) administration reduced cholesterol absorption (control, 54 +/- 7%; AOMA, 26 +/- 8%; P less than 0.0005) and resulted in a 24% increase in apoB-48 synthesis by jejunal enterocytes.
"
2.
Hyperlipidemias (Hyperlipidemia)
07/01/1982 - "
To evaluate AOMA in man, we studied its effects on plasma cholesterol, cholesterol absorption, fecal excretion of cholesterol and its bacterial degradation products, coprostanol and coprostanone, and percent saturation of gallbladder bile with cholesterol in 20 individuals chosen for hyperlipidemia.
"
Related Drugs and Biologics
1.
Cholesterol
2.
surfomer
3.
Apolipoprotein B-48
4.
Cholestanol (Coprostanol)
5.
coprostanone