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HGG 42

used therapeutically in organophosphate poisoning; structure

Also Known As:

HGG-42; Pyridinium, 1-(((3-(cyclohexylcarbonyl)pyridinio)methoxy)methyl)-2-((hydroxyimino)methyl)-, diiodide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridinium Compounds: 5
      - HGG 42: 2

Related Diseases

1.	Poisoning 01/01/1979 - "Therapeutic properties of various combinations of the bispyridinium salts HGG-12 and HGG-42 against soman and sarin poisoning were investigated in male beagles. " 11/01/1983 - "LD50 of 588 mg/kg. Upon comparing ED50 values, HGG-42 was the most effective oxime versus soman and tabun poisoning whereas, HI-6 was the most effective oxime versus sarin poisoning. " 11/01/1983 - "Various oximes (PAM, toxogonin, TMB-4, HS-6, HI-6, HGG-12, HGG-42) combined with atropine were compared as antidotes of soman, sarin and tabun poisoning in non-fasted CD-1 male mice. "
2.	Organophosphate Poisoning 01/01/1979 - "Therapeutic effects of the bis-pyridinium salts HGG-12, HGG-42, and atropine, benactyzine in organophosphate poisoning of dogs."

Related Drugs and Biologics

1.	Soman
2.	Sarin
3.	Atropine
4.	HGG 12
5.	Therapeutic Uses
6.	Salts
7.	Oximes
8.	Obidoxime Chloride (Obidoxime)
9.	Benactyzine
10.	asoxime chloride (H16)