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phenolphthalein glucuronide
RN given refers to parent cpd
Also Known As:
phenolphthalein glucuronide sodium salt
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Phenols: 677
Phenolphthaleins: 2
phenolphthalein glucuronide: 4
Related Diseases
1.
Weight Gain
12/01/1989 - "
Reduced food intake and reduction in weight gain was observed for rats exposed short-term to 1500 ppm dietary Am. Assessment of hepatobiliary function in treated rats indicated that short-term and long-term dietary exposure to Am resulted in a compromised excretion of readily excretable phenolphthalein glucuronide (PG), although inanition may account for this effect in the 1500 ppm group.
"
2.
Necrosis
01/26/1994 - "
Chlordecone (CD) impairs biliary excretion of organic anions (including phenolphthalein glucuronide (PG), imipramine polar metabolites, and taurocholate) without evidence of hepatocellular necrosis in rats.
"
3.
Fistula
06/01/1979 - "
beta-Glucuronidase activity determined in 100 diluted bile samples from 12 rats with bile duct fistula by using phenolphthalein glucuronide as substrate incubated at 56 degrees C and pH 6 was 636 +/- 650 (mean +/- S.D.) modified Sigma units/ml. The enzyme had an optimal pH of 6.0 and was inhibited slightly by cholate by markedly by chenodeoxycholate and deoxycholate.
"
4.
Carcinoma (Carcinomatosis)
12/01/1997 - "
Serum beta-glucuronidase activity was estimated by our modified method using two substrates phenolphthalein glucuronide and p-nitrophenyl glucoronide in 49 healthy subjects and 94 patients with gastrointestinal tract (GIT) carcinoma.
"
12/01/1997 - "
Modified method for determination of serum beta-glucuronidase: A comparative study using P-nitrophenyl glucuronide and phenolphthalein glucuronide as substrate in gastrointestinal tract carcinomas.
"
Related Drugs and Biologics
1.
Glucuronidase
2.
Glucuronides
3.
Cholates
4.
Taurocholic Acid (Sodium Taurocholate)
5.
Chlordecone (Kepone)
6.
Imipramine (Janimine)
7.
Enzymes
8.
Deoxycholic Acid (Sodium Deoxycholate)
9.
Chenodeoxycholic Acid (Chenix)
10.
Anions