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sydnophen
RN given refers to parent cpd; structure in Negwer
Also Known As:
beta-phenylisopropylsydnonimine; sidnofen; sydnophen monohydrochloride; sydnophen, (3-(1-(14)C-methyl))-labeled; 3-(1-methyl-2-phenylethyl)sydnone imine, monohydrochloride
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Oxazoles: 89
Oxadiazoles: 146
Sydnones: 2
sydnophen: 4
Related Diseases
1.
Bradycardia
04/01/1989 - "
The small dose of sydnophen (0.002 micrograms/kg) which wasn't able to cause any alteration of EEG, heart rate and arterial pressure induced decrease of vagal bradycardia.
"
04/01/1989 - "
Intravenous bolus injection of sydnophen (0.002-20 micrograms/kg) resulted in decrease or complete abolition of bradycardia induced by electrical stimulation of vagal peripheral end of anesthetized cats.
"
01/01/1989 - "
The small dose of amphetamine (0.2-0.3 mg/kg) in contrast to sydnophen didn't decrease the vagal bradycardia but even increased it.
"
01/01/1989 - "
The cholinolytic effect of sydnophen discovered in earlier anesthetized cats was confirmed on unanesthetized fish and frogs: the vagal bradycardia induced by electric stimulation of peripheral vagal end was decreased or even abolished by intravenous injection of sydnophen (0.2-20 mg/kg).
"
2.
Delayed Hypersensitivity (Hypersensitivity, Type IV)
05/01/1980 - "
In healthy animals and in those with different experimental tumours, the psychostimulant drug sydnophen activates the immune reactions: increases the number of RFC, the intensity of delayed hypersensitivity, blast transformation of lymphocytes, and the QD coefficient.
"
3.
Alcoholism (Alcohol Abuse)
12/01/1989 - "
The influence of white rats of alcohol abuse formation of immunization by covalent conjugates of serum albumin with psychostimulant sydnophen was investigated.
"
Related Drugs and Biologics
1.
Cholinergic Antagonists (Anticholinergics)
2.
Serum Albumin
3.
Amphetamine (Amfetamine)
Related Therapies and Procedures
1.
Intravenous Injections