8-aminoadenosine

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

1.	Multiple Myeloma 01/01/2011 - "The purine analogue 8-aminoadenosine (8-NH(2)-Ado) is known to be a transcription inhibitor that has proved very effective in multiple myeloma cell lines and primary indolent leukemia cells. " 12/16/2010 - "8-Aminoadenosine (8-NH(2)-Ado), a ribosyl nucleoside analog, in preclinical models of multiple myeloma inhibits phosphorylation of proteins in multiple growth and survival pathways, including Akt. "
2.	Leukemia 01/01/2011 - "The purine analogue 8-aminoadenosine (8-NH(2)-Ado) is known to be a transcription inhibitor that has proved very effective in multiple myeloma cell lines and primary indolent leukemia cells. "
3.	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 12/16/2010 - "8-Aminoadenosine inhibits Akt/mTOR and Erk signaling in mantle cell lymphoma."
4.	Hematologic Neoplasms (Hematological Malignancy) 03/01/2010 - "We report the inhibition of mammalian polyadenylation by the triphosphate derivatives of adenosine analogues, 8-chloroadenosine (8-Cl-Ado) and 8-aminoadenosine (8-amino-Ado), which are under preclinical and clinical investigations for the treatment of hematological malignancies. "
5.	Carcinoma (Carcinomatosis) 01/01/2011 - "8-Aminoadenosine enhances radiation-induced cell death in human lung carcinoma A549 cells."

1.	purine
2.	Proteins (Proteins, Gene)
3.	Nucleosides
4.	Adenosine (Adenocard)
5.	8-chloroadenosine
6.	triphosphoric acid (triphosphate)