YL5084

covalent inhibitor of c-Jun N-terminal protein kinase (JNK) 2/3

Also Known As:

(E)-4-(dimethylamino)-N-(4-((3S,4S)-3-methyl-4-((4-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)pyrimidin-2-yl)amino)pyrrolidine-1-carbonyl)phenyl)but-2-enamide; YL-5084

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - YL5084: 1
  - Pyrrolidines: 115
    - YL5084: 1

Related Diseases

1.	Multiple Myeloma 01/01/2023 - "However, YL5084 exhibited JNK2-independent antiproliferative effects in multiple myeloma cells, suggesting the existence of additional targets relevant in this context. "