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SIM0417

SARS 3-cysteine-like (3CL) protease inhibitor

Also Known As:

SIM 0417; SIM-0417; SSD 8432; SSD-8432; SSD8432

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- SIM0417: 1

Related Diseases

1.	COVID-19 09/01/2023 - "This study aimed to evaluate the efficacy and safety of SIM0417 plus ritonavir (a pharmacokinetic enhancer) in adults with COVID-19. " 09/01/2023 - "Adults with asymptomatic infection, mild or moderate COVID-19 were randomly assigned (3:3:2) to receive either 750 mg SIM0417 plus 100 mg ritonavir, 300 mg SIM0417 plus 100 mg ritonavir or placebo every 12 h for 10 doses. " 09/01/2023 - "Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo-controlled, phase 1b trial."
2.	Asymptomatic Infections 09/01/2023 - "Adults with asymptomatic infection, mild or moderate COVID-19 were randomly assigned (3:3:2) to receive either 750 mg SIM0417 plus 100 mg ritonavir, 300 mg SIM0417 plus 100 mg ritonavir or placebo every 12 h for 10 doses. "

Related Drugs and Biologics

1.	SIM0417
2.	Ritonavir (Norvir)