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GLPG1205

a modulator of GPR84

Also Known As:

9-cyclopropylethynyl-2-((S)-1-(1,4)dioxan-2-ylmethoxy)-6,7-dihydropyrimido(6,1-a)isoquinolin-4-one

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - GLPG1205: 4

Experts

1.	Allamassey, Lisa: 1 article (01/2021)
2.	Desrivot, Julie: 1 article (01/2021)
3.	Helmer, Eric: 1 article (01/2021)
4.	Van Kaem, Tim: 1 article (01/2021)
5.	Chen, Lin-Hai: 1 article (12/2020)
6.	Nan, Fa-Jun: 1 article (12/2020)
7.	Xie, Xin: 1 article (12/2020)
8.	Zhang, Qing: 1 article (12/2020)
9.	Alvey, Luke: 1 article (11/2020)
10.	Blanqué, Roland: 1 article (11/2020)

Related Diseases

1.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/25/2020 - "At once-daily doses of 3 and 10 mg/kg, GLPG1205 reduced disease activity index score and neutrophil infiltration in a mouse dextran sodium sulfate-induced chronic inflammatory bowel disease model, with efficacy similar to positive-control compound sulfasalazine. "
2.	Idiopathic Pulmonary Fibrosis 01/01/2023 - "This study assessed the efficacy, safety and tolerability of GLPG1205 for treatment of idiopathic pulmonary fibrosis (IPF). " 01/01/2023 - "GLPG1205 for idiopathic pulmonary fibrosis: a phase 2 randomised placebo-controlled trial." 01/01/2021 - "GLPG1205 is a novel agent being investigated for the treatment of idiopathic pulmonary fibrosis. " 12/24/2020 - "Although GLPG1205 has failed in a clinical trial for ulcerative colitis, it is undergoing another phase II clinical study for idiopathic pulmonary fibrosis. "
3.	Ulcerative Colitis 12/24/2020 - "Although GLPG1205 has failed in a clinical trial for ulcerative colitis, it is undergoing another phase II clinical study for idiopathic pulmonary fibrosis. "

Related Drugs and Biologics

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3.	sodium sulfate (sodium bisulfate)