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malar rash

Also Known As:
butterfly rash; malar butterfly rash
Networked: 202 relevant articles (11 outcomes, 9 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Arthritis (Polyarthritis)
2. Proteinuria
3. Systemic Lupus Erythematosus (Libman-Sacks Disease)
4. Lupus Nephritis
5. Leukopenia

Experts

1. Sawalha, Amr H: 3 articles (01/2015 - 01/2011)
2. Cavazzana, I: 3 articles (06/2014 - 01/2005)
3. Franceschini, F: 3 articles (06/2014 - 01/2005)
4. Gilkeson, Gary S: 3 articles (01/2012 - 01/2011)
5. Harley, John B: 3 articles (01/2012 - 01/2011)
6. Kamen, Diane L: 3 articles (01/2012 - 01/2011)
7. Kelly, Jennifer A: 3 articles (01/2012 - 01/2011)
8. Levy, Deborah M: 2 articles (01/2022 - 01/2013)
9. Nisihara, Renato: 2 articles (06/2021 - 09/2017)
10. Ramsey-Goldman, Rosalind: 2 articles (12/2020 - 10/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to malar rash:
1. Tacrolimus (Prograf)FDA LinkGeneric
2. Antinuclear AntibodiesIBA
3. DNA (Deoxyribonucleic Acid)IBA
4. Antiphospholipid AntibodiesIBA
08/01/2006 - "She later developed malar rash, oral ulcers, cerebral infarcts with vasculitis and positive ANA, anti-dsDNA, and antiphospholipid antibodies. "
10/01/2015 - "The frequency of the manifestations included in the 1997 ACR criteria was as follows: ANA 97.5%, immunologic disorders (anti-dsDNA, anti-Sm, antiphospholipid antibodies) 85.2%, arthritis 61.8%, haematologic disorders 55.7%, malar rash 31.1%, photosensitivity 29.5%, serositis 27%, renal disorders 27%, oral/nasal ulcers 11.5%, neurologic disorders 8.2%, and discoid rash 5.7%. "
05/01/2006 - "Logistic regression analysis, controlled for age at diagnosis, disease duration and sex, showed that lupus patients included by internists had a higher frequency of malar rash (OR 1.6; 95% CI 1.2-2.2), oral ulcers (OR 1.2; 95% CI 1.4-2.7), neuro-psychiatric manifestations (OR 2.2; 95% CI 1.3- 3.8), kidney disease (OR 1.5; 95% CI 1-2) andantinuclear antibodies (OR 2.1; 95% CI 0.97-4.7), while the frequency of antiphospholipid antibodies (OR 0.6; 95% CI 0.4-0.9) and the number of lupus criteria (P=.002) were lower. "
07/01/2018 - "A 16-year-old girl presenting with polyarthritis, malar rash, and palmar erythema was indicated for steroid therapy on the basis of positive results for antinuclear, anti-Smith, and antiphospholipid antibodies, which confirmed the diagnosis of SLE. "
12/01/2020 - "A few relevant correlations were observed among specific clinical cutaneous manifestations (in particular, malar rash correlated with photosensitivity, alopecia, and oral ulcers) and serologic manifestations (anti-Sm and anti-double-stranded DNA and anti-RNA polymerase, anti-Ro and anti-La, and antiphospholipid antibodies), and these results were validated in the Euro-Lupus cohort. "
5. CreatinineIBA
08/01/1979 - "Patients with Raynaud's phenomenon had a greater incidence of arthritis (P less than 0.02), malar rash (P less than 0.003), and photosensitivity (P less than 0.03), and a lesser incidence of severe renal disease as manifested by serum creatinine over 3.0 mg/dl (P less than 0.007) or creatinine clearance below 60 ml/minute. "
06/01/1999 - "We report about a 27-year-old white male, a known case of class III lupus nephritis with a very high anti-nuclear antibody (ANA) titer, who after 10 years of complete clinical and serological remission presented with sudden development of malar rash, proteinuria and an increase in the serum creatinine. "
11/01/2018 - "She was admitted with malar "butterfly" rash, anasarca and hypertension, associated with an increase in serum creatinine (1.7 mg/dl). "
05/01/2015 - "Variables independently associated with class II included absence of malar rash, negative anti-dsDNA, and ≤5 urine leucocytes/high power field (hpf); with III/IV: age at nephritis diagnosis ≤32 years old, presence of musculoskeletal features, new-onset hypertension, positive anti-dsDNA, >5 urine leucocytes/hpf, creatinine >1.2 mg/dL, cellular casts >1/hpf, and absence of nephrotic range proteinuria; with V: age at nephritis diagnosis >32 years, malar rash, absence of musculoskeletal complaints or serum C3 hypocomplementemia, nephrotic range proteinuria, and ≤9 urine erythrocytes/hpf. "
07/01/1998 - "The MMP-3 levels were significantly higher in SLE patients who had a history of the following abnormalities: persistent proteinuria, cellular casts, anti-double stranded DNA antibodies, decreased C3, decreased creatinine clearance (p < 0.001), circulating immune complex (p < 0.01), malar rash, hypoalbuminemia, or decreased C4 (p < 0.05). "
6. Adrenal Cortex Hormones (Corticosteroids)IBA
7. Hydroxychloroquine (Plaquenil)FDA LinkGeneric
8. SteroidsIBA
9. Chloroquine (Aralen)FDA LinkGeneric
10. SpermidineIBA

Therapies and Procedures

1. Therapeutics
2. Transjugular Intrahepatic Portasystemic Shunt
3. Bone Marrow Transplantation (Transplantation, Bone Marrow)