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GS-441524 monophosphate

a metabolite of remdesivir, precursor to remdesivir triphosphate

Also Known As:

GS 441524 monophosphate; GS-441524-MP; GS441524 monophosphate; remdesivir monophosphate

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleotides: 140
        Adenine Nucleotides: 1066
        Adenosine Monophosphate: 5507
        GS-441524 monophosphate: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Ribonucleotides: 307
    - Adenine Nucleotides: 1066
      - Adenosine Monophosphate: 5507
        GS-441524 monophosphate: 1
  - Purine Nucleotides: 140
    - Adenine Nucleotides: 1066
      - Adenosine Monophosphate: 5507
        GS-441524 monophosphate: 1

Experts

1.	Hansen, Peter Riis: 1 article (01/2021)
2.	Hansen, Poul Erik: 1 article (01/2021)
3.	Jürgens, Gesche: 1 article (01/2021)
4.	Rasmussen, Henrik Berg: 1 article (01/2021)
5.	Taboureau, Olivier: 1 article (01/2021)
6.	Thomsen, Ragnar: 1 article (01/2021)
7.	Zeth, Kornelius: 1 article (01/2021)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2021 - "Similarly, hypoxia and inflammation may lead to reduced expression of adenosine kinase, which is believed to convert GS-441524 to GS-441524 monophosphate, the perceived rate-limiting step in the intracellular formation of GS-441524 triphosphate. "
2.	Hypoxia (Hypoxemia) 01/01/2021 - "Similarly, hypoxia and inflammation may lead to reduced expression of adenosine kinase, which is believed to convert GS-441524 to GS-441524 monophosphate, the perceived rate-limiting step in the intracellular formation of GS-441524 triphosphate. "

Related Drugs and Biologics

1.	Adenosine Kinase
2.	GS-441524
3.	GS-441524 triphosphate