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1-(nitrosooxy)propan-2-ol and 2-(nitrosooxy)propan-1-ol drug combination

a nitric oxide donor

Also Known As:

1-(nitrosooxy)propan-2-ol, 2-(nitrosooxy)propan-1-ol drug combination; PDNO drug; mononitrites Of 1,2-propanediol; nitrosooxypropanol drug

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Alcohols: 595
  - Propanols: 3
    - 2-Propanol: 478
      - 1-(nitrosooxy)propan-2-ol and 2-(nitrosooxy)propan-1-ol drug combination: 3
    - 1-Propanol: 121
      - 1-(nitrosooxy)propan-2-ol and 2-(nitrosooxy)propan-1-ol drug combination: 3
- Nitroso Compounds: 446
  - 1-(nitrosooxy)propan-2-ol and 2-(nitrosooxy)propan-1-ol drug combination: 3

Experts

1.	Nilsson, Kristofer F: 3 articles (01/2020 - 01/2018)
2.	Albert, Johanna: 2 articles (01/2020 - 01/2018)
3.	Frostell, Claes: 2 articles (01/2020 - 01/2018)
4.	Ratajczak, Kornel: 2 articles (01/2020 - 01/2018)
5.	Rodziewicz, Sylwia: 2 articles (01/2020 - 01/2018)
6.	Gustafsson, Lars E: 2 articles (01/2019 - 01/2018)
7.	Barteczko-Grajek, Barbara: 1 article (01/2020)
8.	Gozdzik, Waldemar: 1 article (01/2020)
9.	Göranson, Sofie P: 1 article (01/2020)
10.	Harbut, Piotr: 1 article (01/2020)

Related Diseases

1.	Pulmonary Hypertension 01/01/2020 - "Pulmonary Vasodilation by Intravenous Infusion of Organic Mononitrites Of 1,2-Propanediol in Acute Pulmonary Hypertension Induced by Aortic Cross Clamping and Reperfusion: A Comparison With Nitroglycerin in Anesthetized Pigs." 01/01/2018 - "Organic mononitrites of 1,2-propanediol act as an effective NO-releasing vasodilator in pulmonary hypertension and exhibit no cross-tolerance with nitroglycerin in anesthetized pigs."
2.	Pulmonary Embolism 01/01/2019 - "Therefore, we investigated the effects of a newly developed effective pulmonary vasodilator, the organic mononitrites of 1,2-propanediol (PDNO), in a rabbit model of acute pulmonary embolism. "
3.	Inflammation (Inflammations) 01/01/2020 - "The organic mononitrites of 1,2-propanediol (PDNO), an nitric oxide donor with a very short half-life, are a more efficient pulmonary vasodilator and attenuator of end-organ damage and inflammation without significant side effects compared with nitroglycerin and inorganic nitrite in a porcine SRACC model. "

Related Drugs and Biologics

1.	Vasodilator Agents (Vasodilators)
2.	Nitroglycerin (Dynamite)
3.	Nitric Oxide Donors
4.	Nitrites

Related Therapies and Procedures

1.	Intravenous Infusions