shenling baizhu san

contains herbs: Panax Ginseng, Atractylodes Ovata, Poria Cocos, Dioscorea Batatas, Dolichos lablab, Coix lacryma-jobi, Nelumbo nucifera, Glycyrrhiza uralensis Fisch, Platycodon grandiflorum, and Amomum xanthioides in a ratio of 5 : 5 : 5 : 5 : 4

Networked: 16 relevant articles (6 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Liu, Hui: 2 articles (05/2021 - 11/2019)
2.	Deng, Yuanjun: 2 articles (10/2019 - 01/2019)
3.	Nie, Huan: 2 articles (10/2019 - 01/2019)
4.	Pan, Maoxing: 2 articles (10/2019 - 01/2019)
5.	Tang, Kairui: 2 articles (10/2019 - 01/2019)
6.	Yang, Qinhe: 2 articles (10/2019 - 01/2019)
7.	Zhang, Yupei: 2 articles (10/2019 - 01/2019)
8.	Zheng, Chuiyang: 2 articles (10/2019 - 01/2019)
9.	Chu, Meng-Zhen: 1 article (09/2022)
10.	Ding, Xue-Li: 1 article (09/2022)

Related Diseases

1.	Non-alcoholic Fatty Liver Disease 10/31/2019 - "Lipidomic Analysis of the Protective Effects of Shenling Baizhu San on Non-Alcoholic Fatty Liver Disease in Rats." 10/31/2019 - "Shenling Baizhu San (SLBZS), a famous traditional Chinese medicine, has been demonstrated to exert protective effects against non-alcoholic fatty liver disease (NAFLD), but its exact mechanisms have not been well understood. " 01/01/2019 - "Chinese Herbal Medicine Formula Shenling Baizhu San Ameliorates High-Fat Diet-Induced NAFLD in Rats by Modulating Hepatic MicroRNA Expression Profiles." 01/01/2019 - "The purpose of present study was to investigate the potential mechanism underlying the protective effect of Shenling Baizhu San (SLBZS) on nonalcoholic fatty liver disease (NAFLD) by microRNA (miRNA) sequencing. "
2.	Ulcerative Colitis 01/01/2021 - "Simultaneous Determination of Ten Bioactive Components from Shenling Baizhu San in Rat Plasma by UHPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Two Models of Ulcerative Colitis Rats." 11/15/2019 - "A review of pharmacological and clinical studies on the application of Shenling Baizhu San in treatment of Ulcerative colitis." 06/12/2022 - "Shenling Baizhu San (SBS) is commonly employed to improve gastrointestinal dysfunction in patients with ulcerative colitis (UC) in China. " 01/01/2022 - "Shenling Baizhu San (SLBZS) is reported as an effective drug for ulcerative colitis (UC); however, its effect on intestinal flora remains unknown. " 01/01/2022 - "Effect of Shenling Baizhu San on Intestinal Flora in a Rat Model of Ulcerative Colitis with Spleen Deficiency and Dampness."
3.	Chronic Obstructive Pulmonary Disease (COPD) 05/23/2021 - "Efficacy of Shenling Baizhu San on stable chronic obstructive pulmonary disease patients: A systematic review and meta-analysis." 10/01/2022 - "With the pharmacological effects of regulating immune system, improving lung function and gastrointestinal function, and resisting oxygen, tumor, and inflammation, Shenling Baizhu San is commonly used in modern clinical practice to treat chronic obstructive pulmonary disease, pulmonary fibrosis, bronchial asthma, irritable bowel syndrome, ulcerative colitis, chronic diarrhea, and diabetic, etc. This paper summarized the chemical constituents, pharmacological effects, and clinical application of Shenling Baizhu San in recent years, and predictively analyzed the quality markers of Shenling Baizhu San according to the "five principles" of Q-marker. "
4.	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/01/2020 - "Shenling Baizhu San (SBS), a classical prescription of traditional Chinese medicine, has been proven to be effective in gastrointestinal disorders. " 05/23/2021 - "Shenling Baizhu San (SBS) as a classic Chinese medicine prescription, has been extensively used in gastrointestinal diseases, such as ulcerative colitis and chronic diarrhea. "
5.	Peritoneal Fibrosis 08/01/2023 - "Modified Shenling Baizhu San can improve peritoneal fibrosis induced by PDF with different sugar contents in rats, and the mechanism is related to the changes in the expression of fibrosis markers and ECM accumulation." 08/01/2023 - "To investigate the effect of modified Shenling Baizhu San on the pathological changes and extracellular matrix (ECM) in rats with peritoneal fibrosis induced by peritoneal dialysate fluid (PDF) with different sugar concentration and its mechanism. " 08/01/2023 - "[Intervention of modified Shenling Baizhu San on peritoneal fibrosis induced by peritoneal dialysate with different sugar concentration in rats]." 08/01/2023 - "After the intervention of modified Shenling Baizhu San, compared with the corresponding PDF model groups, the peritoneal fibrosis of rats was improved to varying degrees, and the effect of the 4.25% PDF+traditional Chinese medicine intervention group was more significant, the parietal peritoneum was significantly thinner (μm: 101.86±16.01 vs. 140.65±10.13, P < 0.05), collagen fiber deposition was significantly reduced, peritoneal ultrafiltration volume was significantly increased (mL: -0.01±3.45 vs. -3.53±1.84, P < 0.05), the expressions of E-cadherin and MMP-9 in peritoneal tissues were significantly up-regulated [E-cadherin protein (E-cadherin/β-actin): 0.84±0.08 vs. 0.28±0.05, MMP-9 (A value): 0.60±0.15 vs. 0.37±0.01, both P < 0.05], and the expressions of α-SMA, Vimentin, TIMP-1 and TGF-β1 were significantly down-regulated [α-SMA protein (α-SMA/β-actin): 0.36±0.08 vs. 1.05±0.09, Vimentin protein (Vimentin/β-actin): 0.53±0.07 vs. 1.19±0.04, TIMP-1 (A value): 0.49±0.06 vs. 0.87±0.02, TGF-β1 (A value): 0.67±0.04 vs. 0.89±0.10, all P < 0.05]. "

Related Drugs and Biologics

1.	MicroRNAs (MicroRNA)
2.	Tryptophan (L-Tryptophan)
3.	Mesalamine (Mesalazine)
4.	Tissue Inhibitor of Metalloproteinase-1
5.	Cadherins (E-Cadherin)
6.	Vimentin
7.	Proteins (Proteins, Gene)
8.	Collagen
9.	Polysaccharides (Glycans)
10.	Acids

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Complementary Therapies (Alternative Medicine)