(SYK) inhibitor C61

Also Known As:

1,4-Bis (9-O dihydroquinidinyl) phthalazine-hydroquinidine 1,4-phathalazinediyl diether; 1,4-bis(9-O dihydroquinidinyl)phthalazine hydroquinidine 1,4-phathalazinediyl diether; bis-DPHP cpd; spleen tyrosine kinase (SYK) inhibitor C61

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridazines: 11
    - Phthalazines: 7
      - (SYK) inhibitor C61: 2

Experts

1.	Aktepe, Oktay Halit: 1 article (01/2020)
2.	Sahin, Taha Koray: 1 article (01/2020)
3.	Uckun, Fatih Mehmet: 1 article (01/2020)
4.	Yalcin, Suayib: 1 article (01/2020)
5.	Dibirdik, I: 1 article (10/2010)
6.	Qazi, S: 1 article (10/2010)
7.	Uckun, F M: 1 article (10/2010)

Related Diseases

1.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/01/2010 - "A novel spleen tyrosine kinase (SYK) P-site inhibitor, 1,4-Bis (9-O dihydroquinidinyl) phthalazine/hydroquinidine 1,4-phathalazinediyl diether (C-61), (but not vehicle) markedly enhanced H(2)O(2)-induced apoptosis of primary leukemia cells from each of five relapsed B-lineage acute lymphoblastic leukemia (ALL) patients, as measured by in vitro TUNEL assays. "
2.	Prostatic Neoplasms (Prostate Cancer) 01/01/2020 - "Anti-prostate cancer activity of a nanoformulation of the spleen tyrosine kinase (SYK) inhibitor C61."
3.	Leukemia 10/01/2010 - "A novel spleen tyrosine kinase (SYK) P-site inhibitor, 1,4-Bis (9-O dihydroquinidinyl) phthalazine/hydroquinidine 1,4-phathalazinediyl diether (C-61), (but not vehicle) markedly enhanced H(2)O(2)-induced apoptosis of primary leukemia cells from each of five relapsed B-lineage acute lymphoblastic leukemia (ALL) patients, as measured by in vitro TUNEL assays. "

Related Drugs and Biologics

1.	Syk Kinase