qishen granule

Qishen Granule (QSG) is derived from a traditional Chinese formula named Simiao Yong'an Decoction which is originated from Qing dynasty and composed of 4 herbs: Angelica sinensis, Lonicera japonica, Scrophularia ningpoensis and Glycyrrhiza uralensis.

Also Known As:

Networked: 13 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Li, Chun: 8 articles (03/2022 - 05/2012)
2.	Wang, Yong: 8 articles (03/2022 - 05/2012)
3.	Wang, Wei: 6 articles (01/2022 - 05/2012)
4.	Wang, Qiyan: 5 articles (03/2022 - 01/2019)
5.	Guo, Dongqing: 3 articles (03/2022 - 09/2019)
6.	Sun, Xiaoqian: 3 articles (01/2022 - 01/2019)
7.	Yang, Xiaomin: 3 articles (04/2020 - 09/2019)
8.	Zhang, Qian: 3 articles (04/2020 - 07/2017)
9.	Chen, Xu: 2 articles (03/2022 - 01/2022)
10.	Li, Yanqin: 2 articles (03/2022 - 01/2022)

Related Diseases

1.	Cardiotoxicity 01/01/2022 - "This study is aimed at investigating the cardioprotective effects of Qishen granule (QSG) and the specific mechanism by which QSG alleviates DOX-induced cardiotoxicity (DIC) and providing an alternative for the treatment of DIC. " 01/30/2024 - "Qishen granule attenuates doxorubicin-induced cardiotoxicity by protecting mitochondrial function and reducing oxidative stress through regulation of Sirtuin3." 01/01/2022 - "Qishen Granule Protects against Doxorubicin-Induced Cardiotoxicity by Coordinating MDM2-p53-Mediated Mitophagy and Mitochondrial Biogenesis."
2.	Ischemia 01/01/2022 - "Previous studies have shown that Qishen granule (QSG) can significantly inhibit the inflammatory injury of myocardial tissue caused by ischemia, but its effect and specific mechanism of inhibiting the activation of NLRP3 inflammasome have not been reported. "
3.	Heart Failure 01/01/2022 - "Preliminary clinical and basic researches have proved that Qishen granule (QSG) is an effective prescription for treating heart failure (HF) in China, with a characteristic of regulating the ratio of M1/M2 macrophage in the myocardium. " 01/01/2022 - "Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice." 03/01/2020 - "To comprehensively identify compounds in Qishen granule, which is a widely prescribed herbal formula for treating chronic heart failure, a pseudotargeted screening method was proposed based on compound biosynthetic correlation using ultra high-performance liquid chromatography coupled with high-resolution mass spectrometry. " 01/01/2019 - "Qishen Granule (QSG) is an effective Chinese medicine for treating heart failure. " 07/01/2017 - "To assess the effects of Qishen Granule (, QSG) on sarcoplasmic reticulum (SR) Ca2+ handling in heart failure (HF) model of rats and to explore the underlying molecular mechanisms. "
4.	Myocardial Ischemia (Ischemic Heart Diseases) 04/24/2020 - "Qishen Granule alleviates endoplasmic reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia." 01/01/2022 - "P2X7R-NEK7-NLRP3 Inflammasome Activation: A Novel Therapeutic Pathway of Qishen Granule in the Treatment of Acute Myocardial Ischemia."
5.	Myocardial Infarction 03/01/2022 - "Qishen granule (QSG) is a traditional Chinese medicine formulation that is widely used in clinical practice for the treatment of myocardial infarction (MI), and its efficacy and safety have been well approved. " 03/01/2022 - "Qishen granule (QSG) exerts cardioprotective effects by inhibiting NLRP3 inflammasome and pyroptosis in myocardial infarction rats." 01/01/2020 - "The Protective Effect of Qishen Granule on Heart Failure after Myocardial Infarction through Regulation of Calcium Homeostasis."

Related Drugs and Biologics

1.	Inflammasomes
2.	Dacarbazine (DIC)
3.	Doxorubicin (Adriamycin)
4.	Therapeutic Uses
5.	Calcium

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)