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acumapimod

Also Known As:

3-(5-Amino-4-(3-cyanobenzoyl)-1H-pyrazol-1-yl)-N-cyclopropyl-4-methylbenzamide; Benzamide, 3-(5-amino-4-(3-cyanobenzoyl)-1H-pyrazol-1-yl)-N-cyclopropyl-4-methyl-

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Agyemang, Alex: 1 article (01/2021)
2.	Farrell, Colm: 1 article (01/2021)
3.	Moore, William: 1 article (01/2021)
4.	Parkin, Jacqueline: 1 article (01/2021)
5.	Kobalava, Zhanna D: 1 article (12/2019)
6.	MacKinnon, Alastair: 1 article (12/2019)
7.	Magnusson, Baldur P: 1 article (12/2019)
8.	Parkin, Jacqueline M: 1 article (12/2019)
9.	Strâmbu, Irina R: 1 article (12/2019)

Related Diseases

1.

Chronic Obstructive Pulmonary Disease (COPD)

12/01/2019 - "Phase II Study of Single/Repeated Doses of Acumapimod (BCT197) to Treat Acute Exacerbations of COPD."
12/01/2019 - "Acumapimod is a potent, selective, oral, p38 inhibitor under investigation for treatment of acute exacerbations of COPD (AECOPD). "
01/01/2021 - "Acumapimod, an investigational oral p38 mitogen-activated protein kinase inhibitor for treatment during severe acute exacerbations of chronic obstructive pulmonary disease, is metabolized primarily by cytochrome P450 3A4 (CYP3A4) and is a P-glycoprotein (P-gp) substrate. "

Related Drugs and Biologics

1.	Cytochrome P-450 CYP3A
2.	p38 Mitogen-Activated Protein Kinases
3.	Member 1 Subfamily B ATP Binding Cassette Transporter