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reloxaliase

oxalate-specific enzyme therapy

Also Known As:

ALLN-177

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Lyases: 637
    - Carbon-Carbon Lyases
      - Carboxy-Lyases: 620
        reloxaliase: 3

Experts

1.	Grujic, Danica: 3 articles (01/2021 - 01/2016)
2.	Brettman, Lee: 2 articles (04/2019 - 01/2016)
3.	Easter, Linda: 2 articles (04/2019 - 01/2016)
4.	Langman, Craig B: 2 articles (04/2019 - 01/2016)
5.	Kausz, Annamaria T: 1 article (01/2021)
6.	Keddis, Mira T: 1 article (01/2021)
7.	Knauf, Felix: 1 article (01/2021)
8.	Lieske, John C: 1 article (01/2021)
9.	Pfau, Anja: 1 article (01/2021)
10.	Lingeman, James E: 1 article (04/2019)

Related Diseases

1.

Hyperoxaluria (Oxaluria)

01/01/2021 - "Pilot study of reloxaliase in patients with severe enteric hyperoxaluria and hyperoxalemia."
04/01/2019 - "The results of this pilot study provided justification for further investigation of ALLN-177 in patients with secondary hyperoxaluria. "
01/01/2016 - "ALLN-177 may represent a new approach for managing secondary hyperoxaluria and its complications."
04/01/2019 - "ALLN-177, oral enzyme therapy for hyperoxaluria."
01/01/2016 - "In healthy volunteers, with diet-induced hyperoxaluria treatment with ALLN-177, when compared to placebo, significantly reduced urinary oxalate excretion by degrading dietary oxalate in the gastrointestinal tract and thereby reducing its absorption. "

Related Drugs and Biologics

1.	Oxalates
2.	Calcium
3.	Enzymes
4.	oxalate decarboxylase

Related Therapies and Procedures

1.	Enzyme Therapy