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tricyclic-dimeric-peptide-6

peptide mimetic structurally based on the loop-2 region of the BDNF homodimer that interacts with TrkB

Also Known As:

TDP6

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - tricyclic-dimeric-peptide-6: 1
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - tricyclic-dimeric-peptide-6: 1

Experts

1.	Fletcher, Jessica L: 1 article (01/2019)
2.	Furness, Sebastian G B: 1 article (01/2019)
3.	Murray, Simon S: 1 article (01/2019)
4.	Nguyen, Huynh T H: 1 article (01/2019)
5.	Prawdiuk, Alexa R: 1 article (01/2019)
6.	Wood, Rhiannon J: 1 article (01/2019)
7.	Xiao, Junhua: 1 article (01/2019)

Related Diseases

1.	Demyelinating Diseases (Demyelinating Disease) 01/01/2019 - "Here, we compare two TrkB-targeted BDNF-mimetics, the structural-mimetic, tricyclic dimeric peptide-6 (TDP6) and the non-peptide small molecule TrkB agonist LM22A-4 in a cuprizone model of central demyelination in female mice. "

Related Drugs and Biologics

1.	Brain-Derived Neurotrophic Factor (BDNF)
2.	Peptides (Polypeptides)
3.	Cuprizone
4.	N,N',N'- tris(2- hydroxyethyl)- 1,3,5- benzenetricarboxamide