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fty720-mitoxy

Fingolimod derivative with a beta-triphenylphosphoniumpropanamide

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Sphingosine: 899
      - Fingolimod Hydrochloride: 2395
        fty720-mitoxy: 2
- Alcohols: 595
  - Glycols: 38
    - Propylene Glycols: 2
      - Fingolimod Hydrochloride: 2395
        fty720-mitoxy: 2
  - Amino Alcohols: 20
    - Sphingosine: 899
      - Fingolimod Hydrochloride: 2395
        fty720-mitoxy: 2

Experts

1.	Perez, Ruth G: 2 articles (01/2020 - 01/2020)
2.	Vidal-Martinez, Guadalupe: 2 articles (01/2020 - 01/2020)
3.	Yang, Barbara: 2 articles (01/2020 - 01/2020)
4.	Barragan, Jose A: 1 article (01/2020)
5.	Camarillo, Cynthia: 1 article (01/2020)
6.	Chaparro, Stephanie A: 1 article (01/2020)
7.	Chin, Brandon: 1 article (01/2020)
8.	De-Leon Esquivel, Jocelyn: 1 article (01/2020)
9.	Diaz-Pacheco, Valeria: 1 article (01/2020)
10.	Herrera, Gloria V: 1 article (01/2020)

Related Diseases

1.	Multiple System Atrophy 01/01/2020 - "A Pilot Microbiota Study in Parkinson's Disease Patients versus Control Subjects, and Effects of FTY720 and FTY720-Mitoxy Therapies in Parkinsonian and Multiple System Atrophy Mouse Models." 01/01/2020 - "FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models."
2.	Parkinson Disease (Parkinson's Disease) 01/01/2020 - "A Pilot Microbiota Study in Parkinson's Disease Patients versus Control Subjects, and Effects of FTY720 and FTY720-Mitoxy Therapies in Parkinsonian and Multiple System Atrophy Mouse Models."
3.	Multiple Sclerosis 01/01/2020 - "In mice treated with the approved multiple sclerosis drug, FTY720, or with our FTY720-Mitoxy-derivative, we saw that FTY720 had little effect while FTY720-Mitoxy increased beneficial Ruminococcus and decreased Rickenellaceae family. "
4.	Neuroinflammatory Diseases 01/01/2020 - "FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models."
5.	Synucleinopathies 01/01/2020 - "Our data confirm potent in vivo protection by FTY720-Mitoxy, supporting its further evaluation as a potential therapy for MSA and related synucleinopathies." 01/01/2020 - "FTY720-Mitoxy reduces synucleinopathy and neuroinflammation, restores behavior and mitochondria function, and increases GDNF expression in Multiple System Atrophy mouse models."

Related Drugs and Biologics

1.	Fingolimod Hydrochloride (FTY720)
2.	Glial Cell Line-Derived Neurotrophic Factor (GDNF)

Related Therapies and Procedures

1.	Therapeutics