BIOF2

formulation composed of a corticosteroid, a type of insulin, and organic acids, whose intra-articular application is intended to stimulate cartilage regeneration.

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Delgado-Enciso, Ivan: 2 articles (01/2020 - 10/2018)
2.	Delgado-Enciso, Josuel: 2 articles (01/2020 - 10/2018)
3.	Guzman-Esquivel, Jose: 2 articles (01/2020 - 10/2018)
4.	Martinez-Fierro, Margarita L: 2 articles (01/2020 - 10/2018)
5.	Paz-Garcia, Juan: 2 articles (01/2020 - 10/2018)
6.	Paz-Michel, Brenda: 2 articles (01/2020 - 10/2018)
7.	Preciado-Ramirez, Jorge: 2 articles (01/2020 - 10/2018)
8.	Rodriguez-Sanchez, Iram P: 2 articles (01/2020 - 10/2018)
9.	Valtierra-Alvarez, Jose: 2 articles (01/2020 - 10/2018)
10.	Barajas-Saucedo, Carlos E: 1 article (01/2020)

Related Diseases

1.	Knee Osteoarthritis 10/24/2018 - "The aim of the present study was to evaluate the efficacy and safety of BIOF2 for intra-articular application in patients with severe osteoarthritis of the knee. " 01/01/2020 - "The bioactive cell-free formulation (BIOF2) for cartilage regeneration has shown a major therapeutic response in severe knee osteoarthritis. " 10/24/2018 - "The intra-articular application of the new bioactive cell-free formulation (BIOF2) was well tolerated and showed no significative differences with arthroplasty for the treatment of severe osteoarthritis of the knee. " 01/01/2020 - "To evaluate the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, minimal clinically important improvement (MCII) and sleep disturbances in mild, moderate, and severe stages of knee osteoarthritis (OA) with the novel cell-free formulation treatment (BIOF2). "
2.	Pain (Aches) 01/01/2020 - "BIOF2 generates better patient-reported health outcomes (on pain, stiffness, function, and sleep) in the more severe cases of knee OA." 10/24/2018 - "BIOF2 was well tolerated, causing slight-to-moderate pain only upon application. "
3.	Osteoarthritis 10/24/2018 - "BIOF2 can regenerate articular cartilage and is an easily implemented alternative therapy for the treatment of osteoarthritis. " 01/01/2020 - "To evaluate the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, minimal clinically important improvement (MCII) and sleep disturbances in mild, moderate, and severe stages of knee osteoarthritis (OA) with the novel cell-free formulation treatment (BIOF2). "

Related Therapies and Procedures

1.	Therapeutics
2.	Arthroplasty