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tregalizumab

humanised, monoclonal, anti-CD4 IgG antibody

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Dälken, Benjamin: 2 articles (01/2018 - 12/2016)
2.	Rharbaoui, Faiza: 2 articles (01/2018 - 12/2016)
3.	Aigner, Silke: 1 article (01/2018)
4.	Behrens, Frank: 1 article (01/2018)
5.	Keystone, Edward Clark: 1 article (01/2018)
6.	Knierim, Luise: 1 article (01/2018)
7.	Pacheco-Tena, Cesar: 1 article (01/2018)
8.	Racewicz, Arthur: 1 article (01/2018)
9.	Schmeidl, Rainer: 1 article (01/2018)
10.	Strand, Vibeke: 1 article (01/2018)

Related Diseases

1.

Rheumatoid Arthritis

01/01/2018 - "Efficacy and safety of tregalizumab in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase IIb, randomised, placebo-controlled trial."
12/01/2016 - "The humanized non-depleting anti-CD4 monoclonal antibody Tregalizumab (BT-061) is able to selectively activate the suppressive function of regulatory T cells and has been investigated up to phase IIb in clinical trials in patients suffering from rheumatoid arthritis (RA). "
01/01/2018 - "To evaluate the efficacy, biological activity and safety of tregalizumab in patients with active rheumatoid arthritis (RA) and an inadequate response to methotrexate (MTX). "
12/01/2016 - "High thioredoxin-1 levels in rheumatoid arthritis patients diminish binding and signalling of the monoclonal antibody Tregalizumab."

Related Drugs and Biologics

1.	Methotrexate (Mexate)
2.	Monoclonal Antibodies
3.	Thioredoxins