(E)- N- (4- ((4- methylpiperazin- 1- yl)methyl)- 3- (trifluoromethyl)phenyl)- 3- ((3- (2- (pyridin- 2- yl)vinyl)- 1H- indazol- 6- yl)thio)propanamide

a c-Abl kinase inhibitor

Also Known As:

CHMFL-ABL-121

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 12/05/2018 - "Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia."

1.	Phosphotransferases (Kinase)