Baoyuan decoction

herbal preparation of Astragalus membranaceus (Fisch.) Bunge. (Leguminosae), Panax ginseng C. A. Mey (Araliaceae), Glycyrrhiza uralensis Fisch. (Leguminosae), and Cinnamomum cassia Presl. (Lauraceae) used to treat coronary heart disease, aplastic anemia, and chronic renal faliure; inhibits CYP2C9, CYP2E1, and CYP3A4

Networked: 13 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Jiang, Yong: 12 articles (03/2022 - 03/2016)
2.	Tu, Pengfei: 7 articles (08/2021 - 12/2016)
3.	Tu, Peng-Fei: 5 articles (03/2022 - 03/2016)
4.	Du, Zhiyong: 4 articles (08/2021 - 01/2018)
5.	Guo, Xiaoyu: 4 articles (07/2021 - 12/2016)
6.	Du, Zhi-Yong: 3 articles (03/2022 - 10/2018)
7.	Guo, Xiao-Yu: 3 articles (03/2022 - 10/2018)
8.	Lu, Ying-Yuan: 3 articles (03/2022 - 10/2018)
9.	Wang, Jin-Long: 3 articles (03/2022 - 10/2018)
10.	Li, Chun: 3 articles (08/2021 - 01/2018)

Related Diseases

1.	Heart Failure 04/24/2020 - "Previous studies have approved that Baoyuan decoction (BYD) exerted remarkable cardioprotective effects on heart failure (HF) due to its anti-apoptotic properties. " 03/01/2022 - "Comparative study on the main active components of Baoyuan decoction in plasma and urine of normal and heart failure rats." 04/24/2020 - "Baoyuan decoction ameliorates apoptosis via AT1-CARP signaling pathway in H9C2 cells and heart failure post-acute myocardial infarction rats." 08/01/2021 - "Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction."
2.	Myocardial Infarction 04/24/2020 - "Baoyuan decoction ameliorates apoptosis via AT1-CARP signaling pathway in H9C2 cells and heart failure post-acute myocardial infarction rats." 08/01/2021 - "Baoyuan decoction (BYD) attenuates cardiac hypertrophy through ANKRD1-ERK/GATA4 pathway in heart failure after acute myocardial infarction."
3.	Coronary Disease (Coronary Heart Disease) 10/01/2017 - "Baoyuan decoction (BYD) is a well-known traditional Chinese medicine formula for coronary heart disease with Qi deficiency. " 03/01/2016 - "Baoyuan decoction (BYD) is a classical Chinese formula for coronary heart disease with Qi deficiency, blood stasis tonifying Qi and Yang deficiency. " 12/07/2016 - "As a proof-of-concept, the chemical profiling of Baoyuan decoction (BYD), which is an ancient TCMF that is clinically used for the treatment of coronary heart disease that consists of Ginseng Radix et Rhizoma, Astragali Radix, Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle, and Cinnamomi Cortex, was performed. " 10/28/2018 - "Baoyuan decoction (BYD), a traditional Chinese medicine (TCM) formula, is composed of four herbs and widely used with western drugs to treat coronary heart disease, aplastic anemia and chronic renal failure in clinic. " 04/01/2019 - "Baoyuan decoction (BYD), a well-known traditional Chinese medicine (TCM) formula, is clinically used for the treatment of aplastic anemia, chronic renal failure, coronary heart disease, etc. PURPOSE: The purpose of this study was to develop a large-volume direct injection liquid chromatography-mass spectrometry (LC-MS) method for simultaneous determination of 16 representative flavonoids and saponins in rat plasma after oral administration of BYD. "
4.	Chronic Kidney Failure (Chronic Renal Failure) 10/28/2018 - "Baoyuan decoction (BYD), a traditional Chinese medicine (TCM) formula, is composed of four herbs and widely used with western drugs to treat coronary heart disease, aplastic anemia and chronic renal failure in clinic. " 04/01/2019 - "Baoyuan decoction (BYD), a well-known traditional Chinese medicine (TCM) formula, is clinically used for the treatment of aplastic anemia, chronic renal failure, coronary heart disease, etc. PURPOSE: The purpose of this study was to develop a large-volume direct injection liquid chromatography-mass spectrometry (LC-MS) method for simultaneous determination of 16 representative flavonoids and saponins in rat plasma after oral administration of BYD. "
5.	Aplastic Anemia (Anemia, Hypoplastic) 10/28/2018 - "Baoyuan decoction (BYD), a traditional Chinese medicine (TCM) formula, is composed of four herbs and widely used with western drugs to treat coronary heart disease, aplastic anemia and chronic renal failure in clinic. " 04/01/2019 - "Baoyuan decoction (BYD), a well-known traditional Chinese medicine (TCM) formula, is clinically used for the treatment of aplastic anemia, chronic renal failure, coronary heart disease, etc. PURPOSE: The purpose of this study was to develop a large-volume direct injection liquid chromatography-mass spectrometry (LC-MS) method for simultaneous determination of 16 representative flavonoids and saponins in rat plasma after oral administration of BYD. "

Related Drugs and Biologics

1.	Saponins
2.	Flavonoids
3.	Therapeutic Uses
4.	Isoproterenol (Isoprenaline)
5.	glycyrrhizae radix et rhizoma

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)
2.	Oral Administration