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BC54 compound

selective inhibitor of cAMP-specific PDE4 and PDE7 families

Also Known As:

BC54; ethyl (2Z)-2-(acetylimino)-1-cyclohexyl-5-oxo-1,5-dihydro-2H-dipyrido(1,2- a:2',3'- d)pyrimidine-3-carboxylate

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclohexanes: 3
        BC54 compound: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - BC54 compound: 1
  - Pyridines: 88
    - BC54 compound: 1

Experts

1.	Alaamery, Manal A: 1 article (12/2017)
2.	Allain, Christina: 1 article (12/2017)
3.	Cui, Shuaiying: 1 article (12/2017)
4.	Habara, Alawi: 1 article (12/2017)
5.	Hoffman, Charles S: 1 article (12/2017)
6.	Ivey, F Douglas: 1 article (12/2017)
7.	Le, Cuong: 1 article (12/2017)
8.	Le, Hai: 1 article (12/2017)
9.	Lerner, Adam: 1 article (12/2017)
10.	Morken, James P: 1 article (12/2017)

Related Diseases

1.	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 12/01/2017 - "Consistent with the biological effect of other PDE4 and PDE7 inhibitors, BC54 displays potent anti-inflammatory properties and is superior to a combination of rolipram (a PDE4 inhibitor) and BRL50481 (a PDE7A inhibitor) for inducing apoptosis in chronic lymphocytic leukemia (CLL) cells. "

Related Drugs and Biologics

1.	Phosphodiesterase 4 Inhibitors
2.	Rolipram