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quinuclidin- 3- yl- N- (1- (3- (4- fluorophenyl)phenyl)- 1- methyl- ethyl)carbamate

an inhibitor of glucosylceramide synthase

Also Known As:

GZ667161

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Carbamates: 945
      - quinuclidin-3-yl-N-(1-(3-(4-fluorophenyl)phenyl)-1-methyl-ethyl)carbamate: 1
Heterocyclic Compounds: 198
- Bridged-Ring Heterocyclic Compounds
  - Quinuclidines: 20
    - quinuclidin-3-yl-N-(1-(3-(4-fluorophenyl)phenyl)-1-methyl-ethyl)carbamate: 1

Experts

1.	Cheng, Seng H: 1 article (01/2017)
2.	Clarke, Jennifer: 1 article (01/2017)
3.	Dodge, James C: 1 article (01/2017)
4.	Makino, Elina: 1 article (01/2017)
5.	Marshall, John: 1 article (01/2017)
6.	Olszewski, Maureen A: 1 article (01/2017)
7.	Park, Hyejung: 1 article (01/2017)
8.	Richards, Amy M: 1 article (01/2017)
9.	Sardi, S Pablo: 1 article (01/2017)
10.	Shihabuddin, Lamya S: 1 article (01/2017)

Related Diseases

1.	Memory Disorders (Memory Loss) 01/01/2017 - "Remarkably, treatment with GZ667161 slowed the accumulation of hippocampal aggregates of α-synuclein, ubiquitin, and tau, and improved the associated memory deficits. "
2.	Synucleinopathies 01/01/2017 - "Two murine models of synucleinopathy (a Gaucher-related synucleinopathy model, GbaD409V/D409V and a A53T-α-synuclein overexpressing model harboring wild-type alleles of GBA, A53T-SNCA mouse model) were exposed to a brain-penetrant GCS inhibitor, GZ667161. "

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