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MFM501

synthetically derived pyrrolidone alkaloid; MRSA/dt

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Pyrrolizidine Alkaloids: 290
    - MFM501: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pyrrolizidine Alkaloids: 290
      - MFM501: 1

Experts

1.	Johari, Saiful Azmi: 1 article (01/2017)
2.	Mohamad Ridhwan, Mohamad Jemain: 1 article (01/2017)
3.	Mohamed, Azman: 1 article (01/2017)
4.	Mohammat, Mohd Fazli: 1 article (01/2017)
5.	Mohtar, Mastura: 1 article (01/2017)
6.	Sahdan, Rohana: 1 article (01/2017)
7.	Syed Mohamad, Sharifah Aminah: 1 article (01/2017)

Related Diseases

1.

01/01/2017 - "Previously we have discovered a synthetically derived pyrrolidone alkaloid, MFM501, exhibiting good inhibitory activity against 53 MRSA and MSSA isolates with low cytotoxicity against three normal cell-lines with IC50 values at >625 µg/ml. Time-kill assay, scanning electron microscopy (SEM) analysis, in vivo oral acute toxicity test, and mice peritonitis model were carried out in this study. "

Related Drugs and Biologics

1.	Pyrrolidinones (Pyrrolidones)
2.	Alkaloids