grassystatin F

antineoplastic, potent aspartic protease inhibitor from marine Cyanobacteria; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Triple Negative Breast Neoplasms 11/22/2017 - "Grassystatin F (3) inhibited the cleavage of cystatin C and PAI-1, the activities of their downstream targets cysteine cathepsins and tPA, and the migration of the highly aggressive triple negative breast cancer cells, phenocopying the effect of siRNA-mediated knockdown of cathepsin D."

1.	Cystatin C
2.	Small Interfering RNA (siRNA)
3.	Plasminogen Activator Inhibitor 1
4.	Cysteine (L-Cysteine)
5.	Cathepsins
6.	Cathepsin D