OCLI-023

inhibits both osteoclastogenesis and bone resorption; structure in first source

Also Known As:

N-(2-(methylthio)-6-(4-(pyridin-2-yl)piperazin-1-yl)pyrimidin-4-yl)-1H-indazol-6-amine

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Periodontitis 01/01/2017 - "In a mouse model of periodontitis, ligature induced an increase of distance between cementoenamel junction (CEJ) and alveolar bone crest (ABC) in the second molar, and OCLI-023 significantly reduced it. "
2.	Bone Resorption 01/01/2017 - "OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo."

1.	pyrimidine

1.	Ligation