HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

PF-04236921

targets interleukin-6

Also Known As:

PF 4236921; PF-4236921

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Beebe, Jean: 2 articles (01/2019 - 01/2018)
2.	Li, Cheryl: 2 articles (01/2019 - 01/2018)
3.	Banerjee, Anindita: 1 article (01/2019)
4.	Cataldi, Fabio: 1 article (01/2019)
5.	Comer, Gail M: 1 article (01/2019)
6.	Danese, Silvio: 1 article (01/2019)
7.	Desreumaux, Pierre: 1 article (01/2019)
8.	Fraser, Gerald: 1 article (01/2019)
9.	Hellstern, Paul: 1 article (01/2019)
10.	Kohn, Anna: 1 article (01/2019)

Related Diseases

1.	Crohn Disease (Crohn's Disease) 01/01/2019 - "Crohn's Disease Activity Index (CDAI)-70 response rates with PF-04236921 50 mg were significantly greater than placebo at weeks 8 (49.3% vs 30.6%, P<0.05) and 12 (47.4% vs 28.6%, P<0.05) and met the primary end point. " 01/01/2018 - "The purpose of this study was to characterize pharmacokinetics (PK) of PF-04236921, a novel anti-interleukin-6 monoclonal antibody, and its pharmacokinetic/pharmacodynamic (PK/PD) relationship on serum C-reactive protein (CRP) in healthy volunteers and patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and Crohn's disease (CD). "
2.	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/01/2018 - "The purpose of this study was to characterize pharmacokinetics (PK) of PF-04236921, a novel anti-interleukin-6 monoclonal antibody, and its pharmacokinetic/pharmacodynamic (PK/PD) relationship on serum C-reactive protein (CRP) in healthy volunteers and patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and Crohn's disease (CD). "
3.	Rheumatoid Arthritis 01/01/2018 - "The purpose of this study was to characterize pharmacokinetics (PK) of PF-04236921, a novel anti-interleukin-6 monoclonal antibody, and its pharmacokinetic/pharmacodynamic (PK/PD) relationship on serum C-reactive protein (CRP) in healthy volunteers and patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and Crohn's disease (CD). "

Related Drugs and Biologics

1.	C-Reactive Protein
2.	Monoclonal Antibodies