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bis- (N- monosuccinyl- l- seryl- l- lysine)hexamethylenediamide

Also Known As:

GSB-106

Networked: 8 relevant articles (3 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - bis-(N-monosuccinyl-l-seryl-l-lysine)hexamethylenediamide: 8

Experts

1.	Gudasheva, Tatiana A: 3 articles (12/2021 - 01/2021)
2.	Logvinov, Ilya O: 3 articles (10/2021 - 01/2016)
3.	Seredenin, Sergey B: 3 articles (10/2021 - 01/2016)
4.	Gudasheva, T A: 3 articles (11/2020 - 07/2013)
5.	Seredenin, S B: 3 articles (11/2020 - 07/2013)
6.	Antipova, Tatyana A: 2 articles (10/2021 - 01/2016)
7.	Povarnina, Polina Y: 2 articles (10/2021 - 01/2021)
8.	Antipova, T A: 2 articles (11/2020 - 07/2013)
9.	Kadnikov, Ilya A: 1 article (12/2021)
10.	Kalinina, Tatiana S: 1 article (12/2021)

Related Diseases

1.	Cerebral Infarction 01/01/2016 - "In experimental stroke, the reduction of cerebral infarct volume by GSB-106 (∼66%) was significantly greater than that of GSB-214 (∼28% reduction), which could be explained by the fundamental role of the MAPK/ERK pathway in neurogenesis and neuroplasticity. " 01/01/2021 - "In this work, we studied the GSB-106 effect on the cerebral infarct volume, as well as on neurogenesis and synaptogenesis under the experimental ischemic stroke induced by intravascular occlusion of the middle cerebral artery in rats. "
2.	Anhedonia 10/01/2021 - "At the same time, GSB-106 restored reduced locomotor activity and completely eliminated the anhedonia manifestations. "
3.	Stroke (Strokes) 01/01/2016 - "In experimental stroke, the reduction of cerebral infarct volume by GSB-106 (∼66%) was significantly greater than that of GSB-214 (∼28% reduction), which could be explained by the fundamental role of the MAPK/ERK pathway in neurogenesis and neuroplasticity. "
4.	Hyperalgesia 11/01/2020 - "GSB-106 reduced the severity of some behavioral signs (piloerection, gnashing of teeth, wet-dog shaking, and runaway attempts), but had no effect on mechanical allodynia formed in the rats with dependence. "
5.	Ischemic Stroke 01/01/2023 - "The aim of this work was to study the effects of GSB-106 on depressive-like behavior, cognitive impairments, as well as on hippocampal neuroplasticity in an experimental model of ischemic stroke. " 01/01/2021 - "In this work, we studied the GSB-106 effect on the cerebral infarct volume, as well as on neurogenesis and synaptogenesis under the experimental ischemic stroke induced by intravascular occlusion of the middle cerebral artery in rats. " 01/01/2021 - "Thus, the dimer dipeptide BDNF mimetic GSB-106 exhibits neuroregenerative properties at a clinically relevant time window (24 h) in a model of ischemic stroke presumably due to the stimulation of neurogenesis (and/or gliogenesis) and synaptogenesis." 01/01/2021 - "Neuroregenerative Activity of the Dipeptide Mimetic of Brain-derived Neurotrophic Factor GSB-106 Under Experimental Ischemic Stroke."

Related Drugs and Biologics

1.	Brain-Derived Neurotrophic Factor (BDNF)
2.	Dipeptides
3.	bis- (N- monosuccinyl- l- seryl- l- lysine)hexamethylenediamide
4.	Neuroprotective Agents
5.	Neurotoxins
6.	Antidepressive Agents (Antidepressants)

Related Therapies and Procedures

1.	Aftercare (After-Treatment)