Xenon-129

05/01/2023 - "• The ventilation and gas-exchange imaging with hyperpolarized xenon-129 MRI has enabled the identification of gas-exchange variation between COPD and healthy groups. "
05/01/2023 - "Gas exchange and ventilation imaging of healthy and COPD subjects using hyperpolarized xenon-129 MRI and a 3D alveolar gas-exchange model."
01/01/2021 - "To investigate whether hyperpolarised xenon-129 MRI (HXeMRI) enables regional and physiological resolution of diffusing capacity limitations in chronic obstructive pulmonary disease (COPD), we evaluated 34 COPD subjects and 11 healthy volunteers. "
01/01/2021 - "Characterisation of gas exchange in COPD with dissolved-phase hyperpolarised xenon-129 MRI."
08/01/2019 - "To derive lobar ventilation in patients with chronic obstructive pulmonary disease (COPD) using a rapid time-series hyperpolarized xenon-129 (HPX) magnetic resonance imaging (MRI) technique and compare this to ventilation/perfusion single-photon emission computed tomography (V/Q-SPECT), correlating the results with high-resolution computed tomography (CT) and pulmonary function tests (PFTs). "

07/01/2021 - "The aim of this study was to explore the utility of hyperpolarised xenon-129 (129Xe) ventilation MRI in clinical care and examine its relationship with spirometry and other clinical metrics in people seen in a severe asthma service. "
10/01/2016 - "Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma."

07/01/2023 - "Hyperpolarised xenon-129 diffusion-weighted magnetic resonance imaging for assessing lung microstructure in idiopathic pulmonary fibrosis."
05/01/2023 - "Functional xenon-129 magnetic resonance imaging response to antifibrotic treatment in idiopathic pulmonary fibrosis."
01/01/2021 - "Imaging of the different resonances of dissolved hyperpolarized xenon-129 (129 Xe) in the lung is performed using a four-echo flyback 3D radial spectroscopic imaging technique and is evaluated in healthy volunteers (HV) and subjects with idiopathic pulmonary fibrosis (IPF). "

10/13/2022 - "3D Single-breath Chemical Shift Imaging (3D-SBCSI) is a hybrid MR-spectroscopic imaging modality that uses hyperpolarized xenon-129 gas (Xe-129) to differentiate lung diseases by probing functional characteristics. "
01/01/2019 - "Functional alveolar wall thickness assessed by hyperpolarized xenon-129 MR allows discrimination between healthy subjects and healthy smokers and could become a powerful new measure of early-stage lung disease."
01/01/2019 - "Using Hyperpolarized Xenon-129 MRI to Quantify Early-Stage Lung Disease in Smokers."
01/01/2019 - "Hyperpolarized xenon-129 magnetic resonance (MR) provides sensitive tools that may detect early stages of lung disease in smokers before it has progressed to chronic obstructive pulmonary disease (COPD) apparent to conventional spirometric measures. "
11/07/2022 - "Current PfMRI approaches are dominated by hyperpolarized helium-3 (3He) and xenon-129 (129Xe) gases, which both provide rapid (8-15 s) and well-tolerated imaging examinations in patients with severe pulmonary diseases and pediatric populations, whilst employing no ionizing radiation. "

03/01/2022 - "A pilot study of function-based radiation therapy planning for lung cancer using hyperpolarized xenon-129 ventilation MRI."
11/15/2018 - "Eleven lung cancer patients underwent xenon-129 (129Xe) and helium-3 (3He) ventilation MRI and coregistered proton (1H) anatomic MRI. "