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7-hydroxyl-1-methylindole-3-acetonitrile

has anti-inflammatory activity; structure in first source

Also Known As:

7-HMIA; 7-hydroxy-1-methylindole-3-acetonitrile

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - 7-hydroxyl-1-methylindole-3-acetonitrile: 2

Experts

1.	Cho, Young-Wuk: 1 article (12/2014)
2.	Choi, Hye-Eun: 1 article (12/2014)
3.	Kim, Soo-Dong: 1 article (12/2014)
4.	Lee, Kyung Tae: 1 article (12/2014)
5.	Lee, Yong Sup: 1 article (12/2014)
6.	Shin, Ji-Sun: 1 article (12/2014)

Related Diseases

1.	Edema (Dropsy) 01/25/2023 - "Although we have previously reported the anti-inflammatory effects of 7-hydroxyl-1-methylindole-3-acetonitrile (7-HMIA), a synthesized analog of arvelexin on macrophages and paw edema, its anti-colitis effect and its mechanism are not known. " 12/05/2014 - "Animal studies revealed that 7-HMIA potently suppressed the carrageenan-induced paw edema and myeloperoxidase (MPO) activity in paw tissues. "
2.	Inflammation (Inflammations) 01/25/2023 - "Protective effect of 7-hydroxyl-1-methylindole-3-acetonitrile on the intestinal mucosal damage response to inflammation in mice with DSS-induced colitis."
3.	Colitis 01/25/2023 - "Protective effect of 7-hydroxyl-1-methylindole-3-acetonitrile on the intestinal mucosal damage response to inflammation in mice with DSS-induced colitis." 01/25/2023 - "Although we have previously reported the anti-inflammatory effects of 7-hydroxyl-1-methylindole-3-acetonitrile (7-HMIA), a synthesized analog of arvelexin on macrophages and paw edema, its anti-colitis effect and its mechanism are not known. "

Related Drugs and Biologics

1.	Peroxidase (Myeloperoxidase)
2.	Carrageenan
3.	arvelexin