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bakkenolide-IIIa
neuroprotective cpd from the rhizome of Petasites trichinous; structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Sesquiterpenes: 1370
bakkenolide-IIIa: 1
Experts
1.
Guo, Mei-Li
: 1 article (12/2015)
2.
Jiang, Qian
: 1 article (12/2015)
3.
Li, Run-Ping
: 1 article (12/2015)
4.
Liu, Chong
: 1 article (12/2015)
5.
Tang, Ying
: 1 article (12/2015)
6.
Wang, Ye-Qing
: 1 article (12/2015)
Related Diseases
1.
Brain Infarction
12/01/2015 - "
Bakkenolide-IIIa (4, 8, 16 mg/kg; i.g.) was administered immediately after reperfusion could reduce the brain infarct volume, and the neurological deficit, as well as a high dose of bakkenolide-IIIa, increases the 72 h survival rate in cerebrally damaged rats.
"
2.
Infarction (Infarctions)
12/01/2015 - "
Bakkenolide-IIIa not only inhibited the nuclear translocation of NF-κB in cultured neurons exposed to OGD, but also inhibited the activation of NF-κB in peri-infarct area in cerebrally damaged rats.
"