3,5,4'-tri-O-acetylresveratrol

a resveratrol prodrug with lung protective activity; structure in first source

Networked: 5 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        3,5,4'-tri-O-acetylresveratrol: 5
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - 3,5,4'-tri-O-acetylresveratrol: 5
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Acetates: 4994
      - 3,5,4'-tri-O-acetylresveratrol: 5

Experts

1.	Jin, Faguang: 5 articles (06/2018 - 01/2013)
2.	Liu, Xueying: 5 articles (06/2018 - 01/2013)
3.	Ma, Lijie: 5 articles (06/2018 - 01/2013)
4.	Zhao, Yilin: 4 articles (06/2018 - 01/2013)
5.	Nan, Yandong: 4 articles (01/2016 - 01/2013)
6.	Wang, Ruixuan: 3 articles (06/2018 - 01/2015)
7.	Chen, Tingting: 2 articles (06/2018 - 01/2015)
8.	Chen, Xiangjun: 2 articles (01/2016 - 02/2013)
9.	Liang, Li: 2 articles (01/2016 - 02/2013)
10.	Li, Wangping: 2 articles (01/2015 - 01/2013)

Related Diseases

1.	Lung Injury 01/01/2013 - "3,5,4'-tri-O-acetylresveratrol ameliorates seawater exposure-induced lung injury by upregulating connexin 43 expression in lung." 02/01/2013 - "3,5,4'-Tri-O-acetylresveratrol attenuates seawater aspiration-induced lung injury by inhibiting activation of nuclear factor-kappa B and hypoxia-inducible factor-1α."
2.	Edema (Dropsy) 02/01/2013 - "The results showed that pretreatment with different doses of 3,5,4'-tri-O-acetylresveratrol improved seawater-induced lung histopathologic changes, alleviated lung edema, reduced the production of inflammatory mediators including TNF-α and IL-1β, inhibited MDA activity, and enhanced T-SOD activity, which was possibly associated with inhibition of NF-κB and HIF-1α. "
3.	Acute Lung Injury 01/01/2016 - "The aim of the present study was to evaluate the effects of 3,5,4'-tri-O-acetylresveratrol (AC-Res) on acute lung injury (ALI) induced by seawater inhalation in rats. " 01/01/2016 - "3,5,4'-Tri-O-acetylresveratrol decreases seawater inhalation-induced acute lung injury by interfering with the NF-κB and i-NOS pathways." 01/01/2013 - "The aim of the present study was to examine the effects of 3,5,4'-tri-O-acetylresveratrol on connexin 43 (Cx43) in acute lung injury (ALI) in rats induced by tracheal instillation of artificial seawater. " 02/01/2013 - "The aim of the present study was to investigate the effect of Resveratrol's prodrug: 3,5,4'-tri-O-acetylresveratrol, on seawater drowning-induced acute lung injury (SWD-ALI). "
4.	Drowning 02/01/2013 - "The aim of the present study was to investigate the effect of Resveratrol's prodrug: 3,5,4'-tri-O-acetylresveratrol, on seawater drowning-induced acute lung injury (SWD-ALI). "
5.	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/01/2015 - "The aim of the present research was to investigate the protecting effects of 3,5,4'-tri-O-acetylresveratrol (AC-Rsv) on LPS-induced acute respiratory distress syndrome (ARDS). " 06/01/2018 - "The protecting effects of 3,5,4'-tri-O-acetylresveratrol (AC-Res) on seawater inhalation-induced acute respiratory distress syndrome (ARDS) by interfering with the activation of thioredoxin-1 (Trx-1) pathway were evaluated. " 06/01/2018 - "3,5,4'-Tri-O-acetylresveratrol attenuates seawater inhalation-induced acute respiratory distress syndrome via thioredoxin 1 pathway." 01/01/2015 - "3,5,4'-Tri-O-acetylresveratrol Attenuates Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome via MAPK/SIRT1 Pathway."

Related Drugs and Biologics

1.	Connexin 43 (Connexin43)
2.	Prodrugs
3.	Resveratrol
4.	Sirtuin 1
5.	NF-kappa B (NF-kB)
6.	Thioredoxins
7.	Lipopolysaccharides