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N-methylduloxetine

has analgesic activity

Also Known As:

N-methyl duloxetine

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiophenes: 257
    - Duloxetine Hydrochloride: 1669
      - N-methylduloxetine: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - Duloxetine Hydrochloride: 1669
      - N-methylduloxetine: 1

Experts

1.	Russell, Gabriella: 1 article (03/2016)
2.	Strichartz, Gary R: 1 article (03/2016)
3.	Wang, Chi-Fei: 1 article (03/2016)
4.	Wang, Ging Kuo: 1 article (03/2016)
5.	Wang, Sho-Ya: 1 article (03/2016)

Related Diseases

1.	Postoperative Pain 03/01/2016 - "In addition, both drugs elicited significant use-dependent block of Na currents when stimulated at 5 Hz. R-Duloxetine and N-methyl duloxetine are highly effective against postoperative pain using the skin incision model, and they elicit both tonic and use-dependent block of neuronal Na⁺ channels. "
2.	Pain (Aches) 03/01/2016 - "R-Duloxetine and N-Methyl Duloxetine as Novel Analgesics Against Experimental Postincisional Pain."
3.	Hyperalgesia 03/01/2016 - "Ipsilateral SC injections (2 mg/0.4 mL) of R-duloxetine and N-methyl duloxetine reduced both postoperative allodynia and hyperalgesia by approximately 89% to 99% in the area under the curve of skin responses next to incision over 5 days. "

Related Drugs and Biologics

1.	Duloxetine Hydrochloride (Cymbalta)
2.	Analgesics (Analgesic Drugs)

Related Therapies and Procedures

1.	Injections