Tyr-Pro-Trp-(2-furyl)Map-NH2

Map - alpha-methylene-beta-amino acid; an endomorphin-1 analog with analgesic activity; structure in first source

Also Known As:

MEL1214

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Pain (Aches) 10/01/2015 - "Behavioral studies showed dose-dependent analgesic effect after systematic administration of MEL1214 in the tested pain models. " 10/01/2015 - "MEL1214 shows promise as a suitable compound to treat pain with reduced side effects, and exhibits good potential to be further developed as a novel opioid analgesic in pain treatment. "
2.	Constipation 10/01/2015 - "In contrast to morphine, MEL1214 produced no significant constipation effect at an equivalent dose. "