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muralatin L

from Murraya alata; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        muralatin L: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        muralatin L: 1

Experts

1.	Jiang, Yong: 1 article (01/2016)
2.	Lai, Ren: 1 article (01/2016)
3.	Lv, Hai-Ning: 1 article (01/2016)
4.	Sun, Xiao-Ying: 1 article (01/2016)
5.	Wang, KeWei: 1 article (01/2016)
6.	Wei, Ning-Ning: 1 article (01/2016)
7.	Wu, Yang: 1 article (01/2016)
8.	Yang, Shi-Long: 1 article (01/2016)

Related Diseases

1.

01/08/2016 - "Here, we report the bioassay-guided fractionation and identification of a novel coumarin derivative, named muralatin L, that can specifically activate the nociceptor transient receptor potential vanilloid 1 (TRPV1) channel and reverse the inflammatory pain in mice through channel desensitization. "
01/08/2016 - "Selective Activation of Nociceptor TRPV1 Channel and Reversal of Inflammatory Pain in Mice by a Novel Coumarin Derivative Muralatin L from Murraya alata."
01/08/2016 - "Taken together, our findings show that muralatin L specifically activates TRPV1 and reverses inflammatory pain, thus highlighting the potential of coumarin derivatives from Murraya plants for pharmaceutical and medicinal applications such as pain therapy. "
01/08/2016 - "Furthermore, muralatin L could reverse inflammatory pain induced by formalin and acetic acid in mice but not in TRPV1 knock-out mice. "

Related Drugs and Biologics

1.	Acetic Acid (Vinegar)
2.	Formaldehyde (Formol)
3.	Coumarins

Related Therapies and Procedures

1.	Therapeutics