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2- amino- 2- (2- (4- octylphenyl)ethyl)propane- 1,3- diol phosphonate

has pulmonary barrier protective activity

Also Known As:

(S)-2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol phosphonate; FTY720 S-phosphonate; FTY720 phosphonate

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Dudek, Steven M: 2 articles (01/2022 - 03/2014)
2.	Garcia, Joe G N: 2 articles (01/2022 - 03/2014)
3.	Letsiou, Eleftheria: 2 articles (01/2022 - 03/2014)
4.	Wang, Lichun: 2 articles (01/2022 - 03/2014)
5.	Bandela, Mounica: 1 article (01/2022)
6.	Belvitch, Patrick: 1 article (01/2022)
7.	Brown, Mary E: 1 article (01/2022)
8.	Chen, Jiwang: 1 article (01/2022)
9.	Meliton, Lucille N: 1 article (01/2022)
10.	Wang, Huashan: 1 article (01/2022)

Related Diseases

1.	Acute Lung Injury 01/01/2022 - "MRSA-induced endothelial permeability and acute lung injury are attenuated by FTY720 S-phosphonate." 03/01/2014 - "FTY720 (S)-phosphonate is a promising barrier-promoting agent that effectively maintains sphingosine 1-phosphate receptor 1 levels and improves outcomes in the bleomycin model of acute lung injury." 03/01/2014 - "FTY720 (s)-phosphonate preserves sphingosine 1-phosphate receptor 1 expression and exhibits superior barrier protection to FTY720 in acute lung injury." 03/01/2014 - "FTY720 fails to protect against bleomycin-induced acute lung injury in mice, while FTY720 (S)-phosphonate significantly decreases lung leak and inflammation. "
2.	Inflammation (Inflammations) 03/01/2014 - "FTY720 fails to protect against bleomycin-induced acute lung injury in mice, while FTY720 (S)-phosphonate significantly decreases lung leak and inflammation. "

Related Drugs and Biologics

1.	Bleomycin (Blenoxane)
2.	Sphingosine-1-Phosphate Receptors
3.	Fingolimod Hydrochloride (FTY720)