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FDI-6 compound

inhibits FOXM1; structure in first source

Also Known As:

NCGC00099374

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - FDI-6 compound: 1
  - Pyridines: 88
    - FDI-6 compound: 1
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiophenes: 257
    - FDI-6 compound: 1

Experts

1.	Balasubramanian, Shankar: 1 article (11/2014)
2.	Dexheimer, Thomas S: 1 article (11/2014)
3.	Gormally, Michael V: 1 article (11/2014)
4.	Jadhav, Ajit: 1 article (11/2014)
5.	Lowe, Christopher: 1 article (11/2014)
6.	Maloney, David J: 1 article (11/2014)
7.	Marsico, Giovanni: 1 article (11/2014)
8.	Matak-Vinković, Dijana: 1 article (11/2014)
9.	Michael, Sam: 1 article (11/2014)
10.	Rai, Ganesha: 1 article (11/2014)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 11/12/2014 - "One of the identified compounds, FDI-6 (NCGC00099374), is characterized in depth and is shown to bind directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional downregulation. "

Related Drugs and Biologics

1.	Forkhead Box Protein M1