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N(G),N(G')-dimethylarginine

Also Known As:

N(G),N(G')-dimethyl-L-arginine

Networked: 13 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675

Experts

1.	Tsikas, Dimitrios: 3 articles (09/2015 - 12/2003)
2.	Chan, Wai Ping A: 2 articles (07/2013 - 06/2009)
3.	Heresztyn, Tamila: 2 articles (07/2013 - 06/2009)
4.	Horowitz, John D: 2 articles (07/2013 - 06/2009)
5.	Rajendran, Sharmalar: 2 articles (07/2013 - 06/2009)
6.	Azuma, Hiroshi: 2 articles (06/2002 - 02/2002)
7.	Goto, Moritaka: 2 articles (06/2002 - 02/2002)
8.	Matsuura, Wataru: 1 article (01/2019)
9.	Nakamoto, Kazuo: 1 article (01/2019)
10.	Tokuyama, Shogo: 1 article (01/2019)

Related Diseases

1.	Cardiovascular Diseases (Cardiovascular Disease) 04/01/2012 - "Chronic kidney disease is associated with increased levels of assymetric N(G),N(G)-dimethylarginine (ADMA), which is predictive of increased mortality and cardiovascular disease. " 10/01/2013 - "Dimethylarginine dimethylaminohydrolase (DDAH) acts as an important regulator of vascular function by metabolizing and regulating plasma asymmetric (N(G),N(G)) dimethylarginine (ADMA), a major risk factor for cardiovascular disease. " 08/01/2009 - "Asymmetric dimethylarginine (ADMA, N(G),N(G)-dimethyl-L-arginine) is an endogenous inhibitor of nitric oxide (NO) synthesis, a potential risk factor for cardiovascular diseases and a powerful biochemical parameter in clinical studies. " 12/05/2003 - "Asymmetric dimethylarginine (ADMA; N(G),N(G)-dimethyl-L-arginine) is the most important endogenous inhibitor of nitric oxide synthase and a potential risk factor for cardiovascular diseases. "
2.	Ischemia 12/01/2008 - "Effect of ischemia-reperfusion on renal expression and activity of N(G)-N(G)-dimethylarginine dimethylaminohydrolases." 09/01/2015 - "In the present study, we tested the hypothesis that reduced NO production due to elevated synthesis of N (G),N (G)-dimethyl-L-arginine (asymmetric dimethylarginine, ADMA), an endogenous inhibitor of NO synthesis, is a possible pathophysiological mechanism for progressive intramuscular muscle ischemia and disturbed endothelial function in children with DMD. " 06/01/2002 - "The contents of N(G)-monomethyl-L-arginine (L-NMMA) and asymmetric N(G), N(G)-dimethyl-L-arginine (ADMA) but not L-arginine and symmetric N(G),N'(G)-dimethyl-L-arginine (SDMA) were increased in the cavernosal tissues after ischemia. "
3.	Inflammation (Inflammations) 07/01/2013 - "Inhibition of platelet aggregation by nitric oxide (primary outcome measure), vascular endothelial function, plasma concentrations of N(G), N(G)-dimethyl-L-arginine (ADMA), endothelial progenitor cell count, and high-sensitivity C-reactive protein (markers of endothelial dysfunction and inflammation) were assessed. " 06/01/2009 - "Plasma concentrations of malondialdehyde (MDA), N(G),N(G)-dimethyl-L-arginine (ADMA) and hs-CRP were measured as markers of oxidative stress, endothelial dysfunction and inflammation, respectively. "
4.	Renal Insufficiency (Renal Failure) 07/01/2008 - "Asymmetric N(G),-N(G)-dimethylarginine (ADMA) increases in diseases such as renal failure, diabetes mellitus, and hypercholesterolemia. "
5.	Chronic Renal Insufficiency 04/01/2012 - "Chronic kidney disease is associated with increased levels of assymetric N(G),N(G)-dimethylarginine (ADMA), which is predictive of increased mortality and cardiovascular disease. "

Related Drugs and Biologics

1.	N,N-dimethylarginine (asymmetric dimethylarginine)
2.	Nitric Oxide (Nitrogen Monoxide)
3.	omega-N-Methylarginine (NG Monomethyl L Arginine)
4.	C-Reactive Protein
5.	Arginine (L-Arginine)
6.	Endothelin-1 (Endothelin 1)
7.	Nitric Oxide Synthase (NO Synthase)
8.	Proteins (Proteins, Gene)
9.	Malondialdehyde (Propanedial)
10.	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)