ZINC69391

a Rac1 inhibitor; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Alonso, Daniel F: 1 article (01/2014)
2.	Cardama, Georgina A: 1 article (01/2014)
3.	Ciarlantini, Matias: 1 article (01/2014)
4.	Comin, María Julieta: 1 article (01/2014)
5.	Gandolfi Donadío, Lucia: 1 article (01/2014)
6.	Gomez, Daniel E: 1 article (01/2014)
7.	Gonzalez, Nazareno: 1 article (01/2014)
8.	Menna, Pablo Lorenzano: 1 article (01/2014)

1.	Leukemia 08/04/2022 - "We investigated the inhibition of the signaling molecule ras-related C3 botulinum toxin substrate 1 (Rac1) in leukemia cells derived from 79 consecutive AML patients, using five Rac1 inhibitors: ZINC69391, ITX3, EHOP-016, 1A-116, and NSC23766. "
2.	Glioma (Gliomas) 01/01/2014 - "ZINC69391 reduced cell proliferation, arrested cells in G1 phase, and triggered apoptosis in glioma cells. " 01/01/2014 - "Here we report the effect of ZINC69391, a specific Rac1 inhibitor developed by our group, on human glioma cell lines LN229 and U-87 MG. ZINC69391 is able to interfere with the interaction of Rac1 with Dock180, a relevant Rac1 activator in glioma invasion, and to reduce Rac1-GTP levels. "