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2- (4- bromo- 2,5- dimethoxyphenyl)- N- ((2- methoxyphenyl)methyl)ethanamine

a 2C designer bath salt drug; structure in first source

Also Known As:

25B-NBOMe; 4-bromo-2,5-dimethoxy-N-((2-methoxyphenyl)methyl)benzeneethanamine

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ikegaya, Hiroshi: 1 article (11/2018)
2.	Nakamura, Mami: 1 article (11/2018)
3.	Shintani-Ishida, Kaori: 1 article (11/2018)
4.	Anand, Jacek Sein: 1 article (01/2017)
5.	Aszyk, Justyna: 1 article (01/2017)
6.	Jankowski, Zbigniew: 1 article (01/2017)
7.	Kaliszan, Michał: 1 article (01/2017)
8.	Kot-Wasik, Agata: 1 article (01/2017)
9.	Wiergowski, Marek: 1 article (01/2017)
10.	Wilczewska, Kamila: 1 article (01/2017)

Related Diseases

1.	Rhabdomyolysis 01/01/2017 - "In the present study, we created animal models of rhabdomyolysis using zebrafish larvae to study the pathomechanism of rhabdomyolysis, and demonstrated that 25B-NBOMe can simulate lethal rhabdomyolysis in this animal. " 01/01/2017 - "Recently, we reported the first lethal case of 25B-NBOMe intoxication with severe rhabdomyolysis, concluded by clinical, pathological and toxicological analyses. " 01/01/2017 - "The psychoactive drug 25B-NBOMe recapitulates rhabdomyolysis in zebrafish larvae." 01/01/2017 - "Treatment of the larvae with 25B-NBOMe decreased their survival rate, locomotion, altered birefringence of the skeletal muscle and immunostainings for dystroglycan (a myoseptal protein) and myosin heavy chain (a myofibril protein), which were consistent with rhabdomyolysis. "
2.	Hyperthermia 11/01/2018 - "This study aimed to verify whether 25B-NBOMe induces ambient temperature-dependent hyperthermia and to clarify its mechanism. " 11/01/2018 - "25B-NBOMe administration at 23°C did not change the core body temperature of the rats, whereas administration at 29°C induced significant hyperthermia 30-120 minutes postadministration. " 11/01/2018 - "Our findings indicate that 25B-NBOMe induces hyperthermia at a high ambient temperature via vasoconstriction regulated by 5-HT2A receptors and BAT thermogenesis mediated by decreased levels of plasma serotonin. "
3.	Poisoning 01/15/2017 - "This paper describes cases of poisoning caused by new psychoactive substances such as: 25B-NBOMe (2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine) and 4-CMC (1-(4-chlorophenyl)-2-(methylamino)-1-propanone). "
4.	Hallucinations (Hallucination) 01/15/2017 - "The results of real samples analyses correspond to possible toxicological effects: death resulting from 25B-NBOMe - mediated hallucinations (661ng/mL of 25B-NBOMe and 0.887ng/mL of 4-CMC), fatal overdose of 25B-NBOMe and 4-CMC (66.5ng/mL of 25B-NBOMe and 2.14ng/mL of 4-CMC) and non-fatal intoxication of these drugs (38.4ng/mL of 25B NBOMe and 0.181ng/mL of 4-CMC). "

Related Drugs and Biologics

1.	Dystroglycans (Dystroglycan)
2.	Myosin Heavy Chains (Myosin Heavy Chain)
3.	Serotonin (5 Hydroxytryptamine)
4.	Psychotropic Drugs (Psychoactive Drugs)
5.	Proteins (Proteins, Gene)