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4- (((R)- 1- (benzo(b)thiophene- 3- carbonyl)- 2- methyl- azetidine- 2- carbonyl)- (3- chloro- benzyl)- amino)- butyric acid

structure in first source

Also Known As:

GLPG0974

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Butyrates: 2613
      - 4-(((R)-1-(benzo(b)thiophene-3-carbonyl)-2-methyl-azetidine-2-carbonyl)-(3-chloro-benzyl)-amino)-butyric acid: 2
- Sulfur Compounds: 278
  - Thiophenes: 257
    - 4-(((R)-1-(benzo(b)thiophene-3-carbonyl)-2-methyl-azetidine-2-carbonyl)-(3-chloro-benzyl)-amino)-butyric acid: 2
Lipids: 114793
- Fatty Acids: 27405
  - Volatile Fatty Acids: 3052
    - Butyrates: 2613
      - 4-(((R)-1-(benzo(b)thiophene-3-carbonyl)-2-methyl-azetidine-2-carbonyl)-(3-chloro-benzyl)-amino)-butyric acid: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - 4-(((R)-1-(benzo(b)thiophene-3-carbonyl)-2-methyl-azetidine-2-carbonyl)-(3-chloro-benzyl)-amino)-butyric acid: 2

Experts

1.	Bao, Hongguang: 1 article (01/2022)
2.	Du, Jiayue: 1 article (01/2022)
3.	Guo, Yaoyi: 1 article (01/2022)
4.	Jiang, Li: 1 article (01/2022)
5.	Li, Haojia: 1 article (01/2022)
6.	Liao, Hongsen: 1 article (01/2022)
7.	Si, Yanna: 1 article (01/2022)
8.	Beetens, Johan: 1 article (01/2016)
9.	Galien, René: 1 article (01/2016)
10.	Namour, Florence: 1 article (01/2016)

Related Diseases

1.	Ulcerative Colitis 01/01/2016 - "Based on these results, a proof-of-concept study was initiated to evaluate the safety, tolerability and efficacy of GLPG0974 in patients with mild to moderate ulcerative colitis."
2.	Neuroinflammatory Diseases 01/01/2022 - "However, the GPR43 antagonist, GLPG0974, could reverse the cognitive protective effect and anti-neuroinflammation effect of SCFAs. "