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4- (5- chloro- 2,3- dihydrobenzo(d)thiazol- 2- yl)- 2,6- dimethoxyphenol

a tyrosinase inhibitor; structure in first source

Also Known As:

MHY884

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Pyrogallol: 83
        4-(5-chloro-2,3-dihydrobenzo(d)thiazol-2-yl)-2,6-dimethoxyphenol: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - Benzothiazoles: 40
        4-(5-chloro-2,3-dihydrobenzo(d)thiazol-2-yl)-2,6-dimethoxyphenol: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzothiazoles: 40
      - 4-(5-chloro-2,3-dihydrobenzo(d)thiazol-2-yl)-2,6-dimethoxyphenol: 1

Experts

1.	Choi, Yeon Ja: 1 article (03/2014)
2.	Chung, Hae Young: 1 article (03/2014)
3.	Kim, Seong Jin: 1 article (03/2014)
4.	Kim, So Ra: 1 article (03/2014)
5.	Lee, Hee Won: 1 article (03/2014)
6.	Moon, Hyung Ryong: 1 article (03/2014)
7.	Park, Ji Young: 1 article (03/2014)
8.	Uehara, Yohei: 1 article (03/2014)

Related Diseases

1.

Melanoma (Melanoma, Malignant)

03/01/2014 - "MHY884 suppressed oxidative stress both in vitro and in the melanoma cells in a dose-dependent manner. "
03/01/2014 - "Generation of reactive oxygen species (ROS) and peroxynitrite was measured in vitro and in B16F10 melanoma cells to verify the scavenging activity of MHY884. "
03/01/2014 - "We have previously reported that the synthetic novel compound 4-(5-chloro-2,3-dihydrobenzo[d]thiazol-2-yl)-2,6-dimethoxyphenol (MHY884) strongly suppressed tyrosinase activity and melanin synthesis in B16F10 melanoma cells. "

Related Drugs and Biologics

1.	Peroxynitrous Acid (Peroxynitrite)
2.	Reactive Oxygen Species (Oxygen Radicals)
3.	Monophenol Monooxygenase (Tyrosinase)
4.	Melanins (Melanin)