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subditine

has antineoplastic activity; isolated from Nauclea subdita; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - subditine: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds

Experts

1.	Awang, Khalijah: 1 article (01/2014)
2.	Cheah, Foo Kit: 1 article (01/2014)
3.	Leong, Kok Hoong: 1 article (01/2014)
4.	Liew, Sook Yee: 1 article (01/2014)
5.	Litaudon, Marc: 1 article (01/2014)
6.	Looi, Chung Yeng: 1 article (01/2014)
7.	Mustafa, Mohd Rais: 1 article (01/2014)
8.	Paydar, Mohammadjavad: 1 article (01/2014)
9.	Wong, Won Fen: 1 article (01/2014)

Related Diseases

1.

Prostatic Neoplasms (Prostate Cancer)

01/01/2014 - "Overall, our data demonstrated that the new compound subditine (1) exerts anti-proliferative effect on LNCaP and PC-3 human prostate cancer cells through induction of apoptosis. "
01/01/2014 - "In addition, subditine (1) enhanced intracellular reactive oxygen species (ROS) production, as reflected by increased expression of glutathione reductase (GR) to scavenge damaging free radicals in both prostate cancer cell-lines. "

Related Drugs and Biologics

1.	Reactive Oxygen Species (Oxygen Radicals)
2.	Glutathione Reductase (Glutathione-Disulfide Reductase)
3.	Free Radicals