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4-methoxycarbonyl curcumin

an anti-inflammatory agent that inhibits matrix metalloproteinases

Also Known As:

4-methoxycarbonylcurcumin; CMC 2.5

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Diarylheptanoids: 471
        4-methoxycarbonyl curcumin: 2
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Heptanes: 70
        Diarylheptanoids: 471
        4-methoxycarbonyl curcumin: 2

Experts

1.	Jiao, Junjie: 1 article (10/2021)
2.	Li, Yongli: 1 article (10/2021)
3.	Qi, Yuanzheng: 1 article (10/2021)
4.	Yang, Shihui: 1 article (10/2021)
5.	Yu, Wanqi: 1 article (10/2021)
6.	Zhang, Jingjie: 1 article (10/2021)
7.	Zhao, Jinghui: 1 article (10/2021)
8.	Clemens, McKenzie: 1 article (01/2013)
9.	Golub, Lorne M: 1 article (01/2013)
10.	Gu, Ying: 1 article (01/2013)

Related Diseases

1.	Periodontitis 01/01/2013 - "The therapeutic potential of CMC 2.5 and its congeners may help to prevent tissue damage during various chronic inflammatory diseases including periodontitis and may reduce the risks of systemic diseases associated with this local disorder. " 10/01/2021 - "In addition to natural curcumin, chemically modified curcumin, such as 4-phenylaminocarbonyl bis-demethoxy curcumin (CMC 2.24) and 4-methoxycarbonyl curcumin (CMC 2.5), have also been used in animal models of periodontitis. "
2.	Inflammation (Inflammations) 01/01/2013 - "4-methoxycarbonyl curcumin: a unique inhibitor of both inflammatory mediators and periodontal inflammation." 01/01/2013 - "In the current study, we demonstrate that a novel CMC (CMC 2.5: 4-methoxycarbonyl curcumin) has significant inhibitory effects, better than the parent compound curcumin, on proinflammatory cytokines and MMPs in in vitro, in cell culture, and in an animal model of periodontal inflammation. "

Related Drugs and Biologics

1.	Curcumin
2.	Matrix Metalloproteinases (MMPs)
3.	Cytokines
4.	4-methoxycarbonyl curcumin
5.	demethoxycurcumin