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EM-2-NHNH2

Also Known As:

H-Tyr-Pro-Phe-Phe-NHNH2

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Nerve Tissue Proteins: 2
    - Neuropeptides: 6772
      - EM-2-NHNH2: 1
- Peptides: 82426
  - Neuropeptides: 6772
    - EM-2-NHNH2: 1

Experts

1.	Gu, Ning: 1 article (12/2020)
2.	Wang, Chang-Lin: 1 article (12/2020)
3.	Wang, Meng-Meng: 1 article (12/2020)
4.	Wang, Xiao-Fang: 1 article (12/2020)
5.	Yang, Wen-Jiao: 1 article (12/2020)
6.	Zhang, Yao: 1 article (12/2020)
7.	Zhang, Yu-Zhe: 1 article (12/2020)

Related Diseases

1.	Neuralgia (Stump Neuralgia) 12/01/2020 - "The present study was undertaken to further investigate the spinal anti-allodynic effects of endomorphins (EMs) and their C-terminal hydrazide modified analogs EM-1-NHNH2 and EM-2-NHNH2 in the spared nerve injury (SNI) model of neuropathic pain in mice. " 12/01/2020 - "Our results demonstrated that intrathecal (i.t.) administration of endomorphin-1 (EM-1), endomorphin-2 (EM-2), EM-1-NHNH2 and EM-2-NHNH2 produced potent anti-allodynic effects ipsilaterally in neuropathic pain model. "
2.	Hyperalgesia 12/01/2020 - "However, the anti-allodynia induced by EM-2, but not EM-2-NHNH2 was significantly reduced by both μ1-opioid antagonist, naloxonazine and κ-antagonist, nor-binaltorphamine (nor-BNI), indicating multiple opioid receptors were involved in the anti-allodynic effects of EM-2. "

Related Drugs and Biologics

1.	Hydrazines
2.	EM-1-NHNH2
3.	Opioid Receptors (Opioid Receptor)
4.	endomorphin 2
5.	endomorphin 1
6.	norbinaltorphimine
7.	naloxonazine