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Ocular Motility Disorders (Convergence Insufficiency) Summary

Description: Disorders that feature impairment of eye movements as a primary manifestation of disease. These conditions may be divided into infranuclear, nuclear, and supranuclear disorders. Diseases of the eye muscles or oculomotor cranial nerves (III, IV, and VI) are considered infranuclear. Nuclear disorders are caused by disease of the oculomotor, trochlear, or abducens nuclei in the BRAIN STEM. Supranuclear disorders are produced by dysfunction of higher order sensory and motor systems that control eye movements, including neural networks in the CEREBRAL CORTEX; BASAL GANGLIA; CEREBELLUM; and BRAIN STEM. Ocular torticollis refers to a head tilt that is caused by an ocular misalignment. Opsoclonus refers to rapid, conjugate oscillations of the eyes in multiple directions, which may occur as a parainfectious or paraneoplastic condition (e.g., OPSOCLONUS-MYOCLONUS SYNDROME). (Adams et al., Principles of Neurology, 6th ed, p240)

Also Known As: Convergence Insufficiency; Internuclear Ophthalmoplegia; Eye Motility Disorders; Parinaud's Syndrome; Convergence Excess Show All >>

Networked: 243 relevant articles (15 outcomes, 9 trials/studies) for this Disease

Key Drugs and Agents for Ocular Motility Disorders

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Antibodies : 1 outcome 1 study in 13 results : IBA
  2. Immunoglobulins (Immunoglobulin) : 1 outcome 1 study in 4 results : IBA
  3. Botulinum Toxins (Botulinum Toxin) : 1 outcome in 9 results : IBA
  4. Clonazepam (Rivotril) : 1 outcome in 2 results : FDA 16 Generic
  5. Adrenal Cortex Hormones (Corticosteroids) : 1 outcome in 2 results : IBA
  6. Reserpine (Serpasil) : 1 outcome in 1 result : FDA 101
  7. Propranolol (Inderal) : 1 outcome in 1 result : FDA 158 Generic
  8. Prednisolone (Predate) : 1 outcome in 1 result : FDA 55 Generic
  9. Dexamethasone (Maxidex) : 1 outcome in 1 result : FDA 77 Generic
  10. Baclofen : 1 outcome in 1 result : FDA 31 Generic
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Diseases Related to Ocular Motility Disorders

  1. Neoplasms (Cancer)
  2. Myoclonus (Nocturnal Myoclonus)
  3. Exotropia (Exophoria)
  4. Diplopia (Double Vision)
  5. Deafness (Deaf Mutism)
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Key Therapies for Ocular Motility Disorders

Efficacy Chart >>
  1. Orthoptics (Orthoptic) : 5 outcomes 3 studies in 32 results
  2. Sutures (Suture) : 1 outcome in 6 results
  3. Transplants (Transplant) : 1 outcome in 5 results
  4. Tenotomy : 1 outcome in 3 results
  5. Ventriculostomy : 1 outcome in 2 results
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