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Reperfusion Injury Summary

Description: Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.

Also Known As: Injury, Ischemia-Reperfusion; Injury, Reperfusion; Reperfusion Damage; Damage, Reperfusion; Damages, Reperfusion Show All >>

Networked: 12414 relevant articles (1341 outcomes, 1687 trials/studies) for this Disease

Key Drugs and Agents for Reperfusion Injury

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Nitric Oxide (Nitrogen Monoxide) : 40 outcomes 53 studies in 486 results : FDA 1
  2. Oxygen : 36 outcomes 71 studies in 657 results : IBA
  3. Superoxide Dismutase : 31 outcomes 25 studies in 188 results : IBA
  4. Melatonin : 22 outcomes 15 studies in 95 results : IBA
  5. Adenosine Triphosphate (ATP) : 21 outcomes 26 studies in 208 results : IBA
  6. Adenosine : 20 outcomes 22 studies in 173 results : FDA 19 Generic
  7. Acetylcysteine (Siran) : 17 outcomes 22 studies in 90 results : FDA 17 Generic
  8. Allopurinol (Remid) : 16 outcomes 19 studies in 110 results : FDA 25 Generic
  9. Retinaldehyde (Retinal) : 15 outcomes 29 studies in 126 results : IBA
  10. Phosphotransferases (Kinase) : 15 outcomes 14 studies in 158 results : IBA
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Diseases Related to Reperfusion Injury

  1. Ischemia
  2. Myocardial Ischemia (Ischemic Heart Diseases)
  3. Brain Ischemia (Cerebral Ischemia)
  4. Inflammation
  5. Anoxia (Hypoxia)
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Key Therapies for Reperfusion Injury

Efficacy Chart >>
  1. Transplants (Transplant) : 60 outcomes 59 studies in 712 results
  2. Transplantation (Transplant Recipients) : 33 outcomes 30 studies in 399 results
  3. Lung Transplantation : 25 outcomes 21 studies in 236 results
  4. Homologous Transplantation (Allograft) : 23 outcomes 20 studies in 275 results
  5. Warm Ischemia : 19 outcomes 35 studies in 208 results
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